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Risk variables included SES, stress, conflict, parental depression, parental hostility, support, scaffolding, child negative affect (NA), effortful control (EC), sensory regulation (SR), and attachment security. Model 1 included effects of risk factors at ages 4 and 5 on child depression symptoms at age 6. Model 2 also included depression symptoms at all three ages to examine<jats:italic>changes<\/jats:italic>in these symptoms. Model 1 revealed that age 4 and 5 parental depression, NA, EC, and SR predicted age 6 child depression levels, Several age 4 variables had indirect pathways to age 6 depression via age 5 EC. Model 2 revealed that preschool depression was the only age 4 variable, and EC and SR were the only age 5 variables that significantly predicted increases in age 6 depression. These findings highlight the role of self-regulation in child depression and suggest that targeting self-regulation may be an effective prevention and intervention strategy.<\/jats:p>","DOI":"10.1017\/s0954579418001426","type":"journal-article","created":{"date-parts":[[2019,2,7]],"date-time":"2019-02-07T06:45:42Z","timestamp":1549521942000},"page":"57-71","source":"Crossref","is-referenced-by-count":13,"title":["Multidomain risk factors in early childhood and depression symptoms in 6-year-olds: A longitudinal pathway model"],"prefix":"10.1017","volume":"32","author":[{"given":"Joyce","family":"Hopkins","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen R.","family":"Gouze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John V.","family":"Lavigne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred 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