{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T04:02:15Z","timestamp":1788926535985,"version":"build-2803163510"},"reference-count":53,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2019,6,13]],"date-time":"2019-06-13T00:00:00Z","timestamp":1560384000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dev Psychopathol"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Institutionally deprived young children often display distinctive patterns of attachment, classified as insecure\/other (INS\/OTH), with their adoptive parents. The associations between INS\/OTH and developmental trajectories of mental health and neurodevelopmental symptoms were examined. Age 4 attachment status was determined for 97 Romanian adoptees exposed to up to 24 months of deprivation in Romanian orphanages and 49 nondeprived UK adoptees. Autism, inattention\/overactivity and disinhibited-social-engagement symptoms, emotional problems, and IQ were measured at 4, 6, 11, and 15 years and in young adulthood. Romanian adoptees with over 6 months deprivation (Rom&gt;6) were more often classified as INS\/OTH than UK and Romanian adoptees with less than 6 months deprivation combined. INS\/OTH was associated with cognitive impairment at age 4 years. The interaction between deprivation, attachment status, and age for autism spectrum disorder assessment was significant, with greater symptom persistence in Rom&gt;6 INS\/OTH(+) than other groups. This effect was reduced when IQ at age 4 was controlled for. Age 4 INS\/OTH in Rom&gt;6 was associated with worse autism spectrum disorder outcomes up to two decades later. Its association with cognitive impairment at age 4 is consistent with INS\/OTH being an early marker of this negative developmental trajectory, rather than its cause.<\/jats:p>","DOI":"10.1017\/s0954579419000506","type":"journal-article","created":{"date-parts":[[2019,6,13]],"date-time":"2019-06-13T10:05:05Z","timestamp":1560420305000},"page":"631-640","source":"Crossref","is-referenced-by-count":5,"title":["Adoptees\u2019 responses to separation from, and reunion with, their adoptive parent at age 4 years is associated with long-term persistence of autism symptoms following early severe institutional deprivation"],"prefix":"10.1017","volume":"32","author":[{"given":"Edmund","family":"Sonuga-Barke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Kennedy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"Golm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicky","family":"Knights","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"Kovshoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Kreppner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Kumsta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Maughan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas G.","family":"O'Connor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolff","family":"Schlotz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2019,6,13]]},"reference":[{"key":"S0954579419000506_ref30","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-5834.2010.00550.x"},{"key":"S0954579419000506_ref19","volume-title":"Registrar general's decennial supplement, England and Wales 1961 occupational mortality","year":"1971"},{"key":"S0954579419000506_ref14","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-79948-3_1536"},{"key":"S0954579419000506_ref23","unstructured":"IBM Corp. 2017. 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