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Drawing from psychobiological models implicating aberrant threat sensitivity in the development and maintenance of psychopathology, the current study investigated sensitivity to peer-related social threats as a mechanism underlying the association between peer victimization and anxiety. A sample of 197 dyads of early adolescents (<jats:italic>M<\/jats:italic><jats:sub><jats:italic>age<\/jats:italic><\/jats:sub> = 12.02; 46% female) and parents\/guardians (<jats:italic>M<\/jats:italic><jats:sub><jats:italic>age<\/jats:italic><\/jats:sub> = 41.46; 90% female) completed online surveys assessing peer victimization, sensitivity to potential (i.e., ambiguous) social threats, and anxiety. Controlling for potentially confounding demographic and psychosocial factors, both self- and parent-reported peer victimization were positively associated with adolescent anxiety symptoms. Additionally, there were significant indirect effects from self- and parent-reported peer victimization to anxiety via social threat sensitivity. Supplemental analyses indicated unique effects of covert, but not overt, peer victimization on social threat sensitivity and anxiety. The findings provide initial evidence that peer victimization experiences lower adolescents\u2019 threshold for interpreting threats in ambiguous social situations, which contributes to heightened anxiety. These results implicate social threat sensitivity as a potential therapeutic target for interrupting links from peer victimization to psychological distress.<\/jats:p>","DOI":"10.1017\/s0954579422001018","type":"journal-article","created":{"date-parts":[[2022,10,6]],"date-time":"2022-10-06T12:40:13Z","timestamp":1665060013000},"page":"112-120","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":16,"title":["Facing ambiguity: Social threat sensitivity mediates the association between peer victimization and adolescent anxiety"],"prefix":"10.1017","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8186-7495","authenticated-orcid":false,"given":"Hannah L.","family":"Schacter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0771-6795","authenticated-orcid":false,"given":"Hilary 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