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The aim of the current study was to conduct a meta-analysis to evaluate the correlations between PCEs and adult mental health symptoms. 41 unique studies (\n                    <jats:italic>N<\/jats:italic>\n                    = 74,492) were included. Significant, negative, medium-to-large, effects were observed between PCEs and each mental health symptom (medium-to-large for overall mental health:\n                    <jats:italic>r<\/jats:italic>\n                    = \u2212.268; and depression:\n                    <jats:italic>r<\/jats:italic>\n                    = \u2212.273; for anxiety:\n                    <jats:italic>r<\/jats:italic>\n                    = \u2212.246; and PTSD:\n                    <jats:italic>r<\/jats:italic>\n                    = \u2212.243), indicating that higher levels of PCEs are linked to fewer mental health difficulties in adulthood. Meta-regression analyses identified current age at the time of mental health assessment and adverse childhood experiences (ACEs) as significant moderators. Specifically, the promotive effects of PCEs were stronger among younger adults and weakened with higher ACEs exposure, particularly in relation to overall adult mental health symptoms, depression, PTSD, and anxiety. In contrast, no significant moderation effects were found for sex or the type of PCEs measurement tool used. Integrated prevention frameworks that combine ACEs prevention with PCEs promotion can enhance mental health across the lifespan by addressing both risk and promotive pathways and providing developmentally tailored support.\n                  <\/jats:p>","DOI":"10.1017\/s0954579425100734","type":"journal-article","created":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T08:56:08Z","timestamp":1760086568000},"page":"766-781","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":5,"title":["Positive childhood experiences and adult mental health symptoms: A meta-analysis"],"prefix":"10.1017","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6779-2573","authenticated-orcid":false,"given":"Yijing","family":"Zhang","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/047s2c258","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,10,10]]},"reference":[{"key":"S0954579425100734_ref40","doi-asserted-by":"publisher","DOI":"10.1037\/abn0000040"},{"key":"S0954579425100734_ref54","article-title":"Cyberbullying victimization and mental health symptoms among children and adolescents: A meta-analysis of longitudinal studies","author":"Lee","year":"2025","journal-title":"Trauma, Violence, and Abuse"},{"key":"S0954579425100734_ref91","doi-asserted-by":"publisher","DOI":"10.1177\/0022146510395592"},{"key":"S0954579425100734_ref17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.2008.01979.x"},{"key":"S0954579425100734_ref85","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2021.649911"},{"key":"S0954579425100734_ref103","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph20064746"},{"key":"S0954579425100734_ref74","unstructured":"National Institute of Health (2014). 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