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This study examines the extent to which parent psychopathology mediates the relationship between parent maltreatment history and offspring psychopathology. Using a prospective cohort design, individuals with documented histories of childhood maltreatment (ages 0 \u2013 11 years) during 1967 \u2013 1971 and demographically matched controls were followed into adulthood and first interviewed in 1989-1995 (\n                    <jats:italic>N<\/jats:italic>\n                    = 1,196). Offspring (\n                    <jats:italic>N<\/jats:italic>\n                    = 697, Mage = 22.8 years) were assessed in 2009 \u2013 2010. A general p-factor structure and a model with specific latent constructs were tested. Structural equation modeling was used for mediation. The results indicated that only minor offspring of maltreated parents exhibited more symptoms of depression than offspring of controls. Parent psychopathology predicted offspring psychopathology. Parent depression and dysthymia predicted greater offspring depression, anxiety, PTSD, alcohol use, drug use, and marijuana use. Parent anxiety and alcohol and drug symptoms also predicted offspring alcohol symptoms. There was no evidence that parent psychopathology explained the relationship between a parent\u2019s history of maltreatment and their offspring\u2019s psychopathology. These new results suggest that reconsideration of some assumptions about the intergeneration impacts of maltreatment may be warranted.\n                  <\/jats:p>","DOI":"10.1017\/s0954579425101120","type":"journal-article","created":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T06:58:15Z","timestamp":1769151495000},"page":"1247-1268","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["A prospective investigation of whether parent psychopathology explains the relationship between parent maltreatment and offspring mental health"],"prefix":"10.1017","volume":"38","author":[{"given":"Joanna","family":"Young","sequence":"first","affiliation":[{"name":"Stratton VA Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Harris","sequence":"additional","affiliation":[{"name":"City University of New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kellie","family":"Courtney","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01p9rc392","id-type":"ROR","asserted-by":"publisher"}],"name":"John Jay College, City University of New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7006-4905","authenticated-orcid":false,"given":"Cathy Spatz","family":"Widom","sequence":"additional","affiliation":[{"name":"City University of New York"},{"id":[{"id":"https:\/\/ror.org\/01p9rc392","id-type":"ROR","asserted-by":"publisher"}],"name":"John Jay College, City University of New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,1,23]]},"reference":[{"key":"S0954579425101120_ref19","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.70.1.6"},{"key":"S0954579425101120_ref79","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.117.198721"},{"key":"S0954579425101120_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.chiabu.2016.11.021"},{"key":"S0954579425101120_ref40","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2024.0804"},{"key":"S0954579425101120_ref14","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579400006167"},{"key":"S0954579425101120_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(19)30369-4"},{"key":"S0954579425101120_ref78","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291712001298"},{"key":"S0954579425101120_ref121","doi-asserted-by":"publisher","DOI":"10.1017\/S095457942300055X"},{"key":"S0954579425101120_ref13","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579409000285"},{"key":"S0954579425101120_ref52","doi-asserted-by":"publisher","DOI":"10.1037\/abn0000258"},{"key":"S0954579425101120_ref75","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.114.149591"},{"key":"S0954579425101120_ref110","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291707002073"},{"key":"S0954579425101120_ref54","volume-title":"Children\u2019s depression inventory: Technical manual update","author":"Kovacs","year":"2003"},{"key":"S0954579425101120_ref34","doi-asserted-by":"publisher","DOI":"10.1177\/0192513X13477411"},{"key":"S0954579425101120_ref61","first-page":"1111","article-title":"The effects of parental mood on reports of their children\u2019s psychopathology","volume":"53","author":"Maoz","year":"2014","journal-title":"Journal of the American Academy of Child and Adolescent Psychiatry"},{"key":"S0954579425101120_ref2","volume-title":"Diagnostic and statistical manual of mental health disorders (DSM-III-R)","year":"1987"},{"key":"S0954579425101120_ref44","unstructured":"Harris, K. 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