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In spite of culture-proven diagnosis and appropriate treatment of the mother with antibiotics, fetal loss occurred at 16 weeks of gestation. <jats:italic>Salmonella typhi<\/jats:italic> was found in the fetal lung on autopsy, consistent with vertical transmission of the organism. None of the clinicians caring for the patient had imagined that gram-negative bacteria could cross the placenta and kill the fetus in spite of early diagnosis and treatment with appropriate antibiotics.<\/jats:p>","DOI":"10.1017\/s0965539515000066","type":"journal-article","created":{"date-parts":[[2015,8,5]],"date-time":"2015-08-05T02:53:22Z","timestamp":1438743202000},"page":"332-338","source":"Crossref","is-referenced-by-count":24,"title":["INTRACELLULAR ORGANISMS AS PLACENTAL INVADERS"],"prefix":"10.1017","volume":"25","author":[{"given":"MARGUERITE B.","family":"VIGLIANI","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANNA I.","family":"BAKARDJIEV","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2015,8,5]]},"reference":[{"key":"S0965539515000066_ref009","first-page":"216","article-title":"Congenital listeriosis: diagnosis from placental studies","volume":"20","author":"Driscoll","year":"1962","journal-title":"Oncologia"},{"key":"S0965539515000066_ref012","doi-asserted-by":"publisher","DOI":"10.1086\/430090"},{"key":"S0965539515000066_ref016","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.15.6808-6820.2000"},{"key":"S0965539515000066_ref008","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1960.tb04731.x"},{"key":"S0965539515000066_ref021","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2003.09.010"},{"key":"S0965539515000066_ref001","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/973297"},{"key":"S0965539515000066_ref017","doi-asserted-by":"publisher","DOI":"10.1126\/science.1220030"},{"key":"S0965539515000066_ref023","doi-asserted-by":"publisher","DOI":"10.3201\/eid1905.13997"},{"key":"S0965539515000066_ref020","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-014-0449-1"},{"key":"S0965539515000066_ref013","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000732"},{"key":"S0965539515000066_ref024","doi-asserted-by":"publisher","DOI":"10.1515\/jpm.2011.035"},{"key":"S0965539515000066_ref004","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.3.1344-1350.2001"},{"key":"S0965539515000066_ref019","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002005"},{"key":"S0965539515000066_ref015","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.102.004325"},{"key":"S0965539515000066_ref005","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1038\/44593","article-title":"Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes","volume":"401","author":"Vazquez-Torres","year":"1999","journal-title":"Nature"},{"key":"S0965539515000066_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2008.04.018"},{"key":"S0965539515000066_ref010","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(77)90661-5"},{"key":"S0965539515000066_ref011","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.01.018"},{"key":"S0965539515000066_ref018","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0020066"},{"key":"S0965539515000066_ref014","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.05899-11"},{"key":"S0965539515000066_ref002","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2011.11.006"},{"key":"S0965539515000066_ref022","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2011.10-0589"},{"key":"S0965539515000066_ref006","doi-asserted-by":"publisher","DOI":"10.1016\/j.jri.2012.10.015"},{"key":"S0965539515000066_ref007","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.2004.00170.x"}],"container-title":["Fetal and Maternal Medicine Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0965539515000066","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T08:17:16Z","timestamp":1752135436000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0965539515000066\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":24,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["S0965539515000066"],"URL":"https:\/\/doi.org\/10.1017\/s0965539515000066","relation":{},"ISSN":["0965-5395","1469-5065"],"issn-type":[{"value":"0965-5395","type":"print"},{"value":"1469-5065","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11]]}}}