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The CaM intracellular localization was not affected by gap junction's downregulation and CaM inhibition did not completely abolished the endocytic activity of oocytes. We showed that cAMP was able to completely rescue the endocytic competence in follicles in which gap junctional communication had been disrupted by octanol. Moreover cAMP was capable of restoring oocyte endocytic capability in the presence of octanol and stelazine, a CaM inhibitor. We propose that, in Vtg uptake regulation, cAMP is upstream of CaM during the endocytic signalling pathway.<\/jats:p>","DOI":"10.1017\/s0967199411000207","type":"journal-article","created":{"date-parts":[[2011,5,4]],"date-time":"2011-05-04T12:52:15Z","timestamp":1304513535000},"page":"1-9","source":"Crossref","is-referenced-by-count":6,"title":["Involvement of cAMP and calmodulin in endocytic yolk uptake during<i>Xenopus laevis<\/i>oogenesis"],"prefix":"10.1017","volume":"21","author":[{"given":"Melchor Emilio","family":"Luque","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda de los Angeles","family":"Serrano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Eugenia","family":"M\u00f3naco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evelina In\u00e9s","family":"Villecco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara Serafina","family":"S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2011,5,4]]},"reference":[{"key":"S0967199411000207_ref26","doi-asserted-by":"crossref","first-page":"14779","DOI":"10.1016\/S0021-9258(18)47863-5","article-title":"The intracellular fate of vitellogenin in Xenopus oocytes is determined by its extracellular concentration during endocytosis","volume":"262","author":"Wall","year":"1987","journal-title":"J. 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