{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:45:25Z","timestamp":1786999525263,"version":"build-2736575974"},"reference-count":40,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T00:00:00Z","timestamp":1735516800000},"content-version":"vor","delay-in-days":333,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["intpsychogeriatrics.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Psychogeriatrics"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1017\/s1041610223000455","type":"journal-article","created":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T03:12:14Z","timestamp":1685070734000},"page":"142-148","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Benzodiazepine use and risk of incident MCI and dementia in a community sample"],"prefix":"10.1016","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1340-7649","authenticated-orcid":false,"given":"Esther G.","family":"Teverovsky","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariel","family":"Gildengers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinhui","family":"Ran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin","family":"Jacobsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung-Chou H.","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2762-7105","authenticated-orcid":false,"given":"Mary","family":"Ganguli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1017\/S1041610223000455_bb0010","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.medcli.2020.02.006","article-title":"|Association between benzodiazepine use and development of dementia","volume":"156","author":"Aldaz","year":"2021","journal-title":"Medicina Clinica"},{"key":"10.1017\/S1041610223000455_bb0015","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.jagp.2012.09.010","article-title":"Old worries and new anxieties: behavioral symptoms and mild cognitive impairment in a population study","volume":"22","author":"Andreescu","year":"2014","journal-title":"The American Journal of Geriatric Psychiatry"},{"key":"10.1017\/S1041610223000455_bb0020","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.jamda.2019.08.017","article-title":"Uncertain association between benzodiazepine use and the risk of dementia: a cohort study","volume":"21","author":"Baek","year":"2020","journal-title":"Journal of the American Medical Directors Association"},{"key":"10.1017\/S1041610223000455_bb0025","doi-asserted-by":"crossref","first-page":"e6231","DOI":"10.1136\/bmj.e6231","article-title":"Benzodiazepine use and risk of dementia: prospective population based study","volume":"345","author":"Billioti de Gage","year":"2012","journal-title":"BMJ"},{"key":"10.1017\/S1041610223000455_bb0030","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0005-7967(92)90093-V","article-title":"Psychometric properties of the Penn state worry questionnaire in a clinical anxiety disorders sample","volume":"30","author":"Brown","year":"1992","journal-title":"Behaviour Research and Therapy"},{"key":"10.1017\/S1041610223000455_bb0035","doi-asserted-by":"crossref","first-page":"zsaa260","DOI":"10.1093\/sleep\/zsaa260","article-title":"Comparative efficacy and safety of hypnotics for insomnia in older adults: a systematic review and network meta-analysis","volume":"44","author":"Chiu","year":"2021","journal-title":"Sleep"},{"key":"10.1017\/S1041610223000455_bb0040","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1017\/S0033291703008213","article-title":"Older adults and withdrawal from benzodiazepine hypnotics in general practice: effects on cognitive function, sleep, mood and quality of life","volume":"33","author":"Curran","year":"2003","journal-title":"Psychological Medicine"},{"key":"10.1017\/S1041610223000455_bb0045","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.neurobiolaging.2019.08.008","article-title":"Benzodiazepine use and brain amyloid load in nondemented older individuals: a florbetapir PET study in the Multidomain Alzheimer Preventive Trial cohort","volume":"84","author":"Desmidt","year":"2019","journal-title":"Neurobiology of Aging"},{"key":"10.1017\/S1041610223000455_bb0050","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1002\/gps.5598","article-title":"Long-term anticholinergic, benzodiazepine and Z-drug use in community-dwelling older adults: What is the impact on cognitive and neuropsychological performance?","volume":"36","author":"Dyer","year":"2021","journal-title":"International Journal of Geriatric Psychiatry"},{"key":"10.1017\/S1041610223000455_bb0055","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s41999-021-00553-w","article-title":"Is there a link between the use of benzodiazepines and related drugs and dementia? A systematic review of reviews","volume":"13","author":"Ferreira","year":"2022","journal-title":"European Geriatric Medicine"},{"key":"10.1017\/S1041610223000455_bb0060","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"Mini-mental state\u201d: a practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"Journal of Psychiatric Research"},{"key":"10.1017\/S1041610223000455_bb0065","doi-asserted-by":"crossref","first-page":"777404","DOI":"10.3389\/fnagi.2021.777404","article-title":"Impaired cognitive function and hippocampal changes following chronic diazepam treatment in middle-aged mice","volume":"13","author":"Furukawa","year":"2021","journal-title":"Frontiers in Aging Neuroscience"},{"key":"10.1017\/S1041610223000455_bb0070","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1136\/jech-2011-200314","article-title":"Benzodiazepine use and risk of dementia: evidence from the Caerphilly Prospective Study (CaPS)","volume":"66","author":"Gallacher","year":"2012","journal-title":"Journal of Epidemiology and Community Health"},{"key":"10.1017\/S1041610223000455_bb0075","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1097\/JGP.0b013e3181cdee4f","article-title":"Prevalence of mild cognitive impairment by multiple classifications: the Monongahela-Youghiogheny Healthy Aging Team (MYHAT) project","volume":"18","author":"Ganguli","year":"2010","journal-title":"The American Journal of Geriatric Psychiatry"},{"key":"10.1017\/S1041610223000455_bb0080","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1097\/WAD.0000000000000004","article-title":"Vascular risk factors and cognitive decline in a population sample","volume":"28","author":"Ganguli","year":"2014","journal-title":"Alzheimer Disease & Associated Disorders"},{"key":"10.1017\/S1041610223000455_bb0085","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/00019442-199500320-00006","article-title":"Depressive symptoms and associated factors in a rural elderly population: the MoVIES project","volume":"3","author":"Ganguli","year":"1995","journal-title":"The American Journal of Geriatric Psychiatry"},{"key":"10.1017\/S1041610223000455_bb0090","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1111\/jgs.15642","article-title":"Mild cognitive impairment that does not progress to dementia: a population-based study","volume":"67","author":"Ganguli","year":"2019","journal-title":"Journal of the American Geriatrics Society"},{"key":"10.1017\/S1041610223000455_bb0095","first-page":"1035","article-title":"Use of benzodiazepines and risk of incident dementia: a retrospective cohort study","volume":"77","author":"Gerlach","year":"2021","journal-title":"The Journals of Gerontology: Series A"},{"key":"10.1017\/S1041610223000455_bb0100","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1001\/archpsyc.58.7.681","article-title":"Early coadministration of clonazepam with sertraline for panic disorder","volume":"58","author":"Goddard","year":"2001","journal-title":"Archives of General Psychiatry"},{"key":"10.1017\/S1041610223000455_bb0105","doi-asserted-by":"crossref","first-page":"801","DOI":"10.3233\/JAD-151006","article-title":"Regular benzodiazepine and Z-substance use and risk of dementia: an analysis of German claims data","volume":"54","author":"Gomm","year":"2016","journal-title":"Journal of Alzheimer\u2019s Disease"},{"key":"10.1017\/S1041610223000455_bb0110","doi-asserted-by":"crossref","first-page":"i90","DOI":"10.1136\/bmj.i90","article-title":"Benzodiazepine use and risk of incident dementia or cognitive decline: prospective population based study","volume":"352","author":"Gray","year":"2016","journal-title":"BMJ"},{"key":"10.1017\/S1041610223000455_bb0115","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1186\/s12877-019-1280-2","article-title":"Anticholinergic and benzodiazepine medication use and risk of incident dementia: a UK cohort study","volume":"19","author":"Grossi","year":"2019","journal-title":"BMC Geriatrics"},{"key":"10.1017\/S1041610223000455_bb0120","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.jamda.2019.05.010","article-title":"Association of benzodiazepine and anticholinergic drug usage with incident dementia: a prospective cohort study of community-dwelling older adults","volume":"21","author":"Hafdi","year":"2020","journal-title":"Journal of the American Medical Directors Association"},{"key":"10.1017\/S1041610223000455_bb0125","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.jpsychires.2017.11.012","article-title":"What can predict and prevent the long-term use of benzodiazepines?","volume":"97","author":"Hata","year":"2018","journal-title":"Journal of Psychiatric Research"},{"key":"10.1017\/S1041610223000455_bb0130","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1017\/S1041610217000473","article-title":"The prevalence and progression of mild cognitive impairment among clinic and community populations: a systematic review and meta-analysis","volume":"29","author":"Hu","year":"2017","journal-title":"International Psychogeriatrics"},{"key":"10.1017\/S1041610223000455_bb0135","first-page":"e12309","article-title":"Benzodiazepine use and the risk of dementia","volume":"8","author":"Joyce","year":"2022","journal-title":"Alzheimer\u2019s & Dementia: Translational Research & Clinical Interventions"},{"key":"10.1017\/S1041610223000455_bb0140","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1093\/ageing\/afn277","article-title":"The risk of cognitive impairment in older community-dwelling women after benzodiazepine use","volume":"38","author":"Lagnaoui","year":"2008","journal-title":"Age and Ageing"},{"key":"10.1017\/S1041610223000455_bb0145","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.jad.2020.08.025","article-title":"Association between concurrent antidepressant and hypnotic treatment and the risk of dementia: a nationwide cohort study","volume":"277","author":"Lin","year":"2020","journal-title":"Journal of Affective Disorders"},{"key":"10.1017\/S1041610223000455_bb0150","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1002\/phar.2170","article-title":"Association between development of dementia and use of benzodiazepines: a systematic review and meta-analysis","volume":"38","author":"Lucchetta","year":"2018","journal-title":"Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy"},{"key":"10.1017\/S1041610223000455_bb0155","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1111\/j.1600-0447.2008.01326.x","article-title":"Rate of progression of mild cognitive impairment to dementia \u2013 meta-analysis of 41 robust inception cohort studies","volume":"119","author":"Mitchell","year":"2009","journal-title":"Acta Psychiatrica Scandinavica"},{"key":"10.1017\/S1041610223000455_bb0160","first-page":"35","article-title":"A systematic review and meta-analysis of the risk of dementia associated with benzodiazepine use, after controlling for protopathic bias","author":"Mitra","year":"2022"},{"key":"10.1017\/S1041610223000455_bb0165","doi-asserted-by":"crossref","first-page":"2412","DOI":"10.1212\/WNL.43.11.2412-a","article-title":"Current vision and scoring rules the clinical dementia rating (CDR)","volume":"43","author":"Morris","year":"1993","journal-title":"Neurology"},{"key":"10.1017\/S1041610223000455_bb0170","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1212\/WNL.46.3.700","article-title":"Age and education correction of Mini-Mental State Examination for English-and Spanish-speaking elderly","volume":"46","author":"Mungas","year":"1996","journal-title":"Neurology"},{"key":"10.1017\/S1041610223000455_bb0175","doi-asserted-by":"crossref","first-page":"1569456","DOI":"10.1155\/2020\/1569456","article-title":"Is long-term benzodiazepine use a risk factor for cognitive decline? Results of a systematic review","volume":"2020","author":"Nader","year":"2020","journal-title":"Journal of Addiction"},{"key":"10.1017\/S1041610223000455_bb0180","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1177\/1060028019882037","article-title":"Is benzodiazepine use associated with the risk of dementia and cognitive impairment-not dementia in older persons? The Canadian Study of Health and Aging","volume":"54","author":"Nafti","year":"2020","journal-title":"Annals of Pharmacotherapy"},{"key":"10.1017\/S1041610223000455_bb0185","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s40263-018-0535-3","article-title":"A systematic review and meta-analysis of the risk of dementia associated with benzodiazepine use, after controlling for protopathic bias","volume":"32","author":"Penninkilampi","year":"2018","journal-title":"CNS Drugs"},{"key":"10.1017\/S1041610223000455_bb0190","doi-asserted-by":"crossref","first-page":"e1002254","DOI":"10.1371\/journal.pmed.1002254","article-title":"APOE-related risk of mild cognitive impairment and dementia for prevention trials: an analysis of four cohorts","volume":"14","author":"Qian","year":"2017","journal-title":"PLoS Medicine"},{"key":"10.1017\/S1041610223000455_bb0195","series-title":"A Language and Environment For Statistical Computing","author":"R-Core-Team","year":"2020"},{"key":"10.1017\/S1041610223000455_bb0200","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1177\/014662167700100306","article-title":"The CES-D Scale: a self-report depression scale for research in the general population","volume":"1","author":"Radloff","year":"1977","journal-title":"Applied Psychological Measurement"},{"key":"10.1017\/S1041610223000455_bb0205","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.jalz.2015.10.006","article-title":"Benzodiazepine, psychotropic medication, and dementia: a population-based cohort study","volume":"12","author":"Shash","year":"2016","journal-title":"Alzheimer\u2019s & Dementia"}],"container-title":["International Psychogeriatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1041610224029661?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1041610224029661?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1041610223000455","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T01:21:12Z","timestamp":1736472072000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1041610224029661"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":40,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["S1041610224029661"],"URL":"https:\/\/doi.org\/10.1017\/s1041610223000455","relation":{},"ISSN":["1041-6102"],"issn-type":[{"value":"1041-6102","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Benzodiazepine use and risk of incident MCI and dementia in a community sample","name":"articletitle","label":"Article Title"},{"value":"International Psychogeriatrics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1017\/S1041610223000455","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2023 The Author(s), 2023. Published by Cambridge University Press on behalf of International Psychogeriatric Association. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}