{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T20:51:02Z","timestamp":1759092662923},"reference-count":6,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2008,8,19]],"date-time":"2008-08-19T00:00:00Z","timestamp":1219104000000},"content-version":"unspecified","delay-in-days":3883,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[1998,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Formation of thrombus in the heart is a rare event in children. Genetic risk factors determined for thrombophilia with additional exogenous risk factors may, none the less, promote cardiac thrombosis. We report on a boy without predisposing cardiac disease, heterozygous for resistance to activated protein C, who developed multiple thrombuses attached to the mitral valve which led to recurrent arterial throm boembolism. In addition this patient showed enhanced levels of lipoprotein (a).<\/jats:p>","DOI":"10.1017\/s1047951100004741","type":"journal-article","created":{"date-parts":[[2008,8,31]],"date-time":"2008-08-31T20:26:11Z","timestamp":1220214371000},"page":"116-118","source":"Crossref","is-referenced-by-count":4,"title":["Intracardiac thrombus associated with resistance to activated protein C"],"prefix":"10.1017","volume":"8","author":[{"given":"Bernd","family":"Kohlhase","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deniz","family":"Kececioglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrike","family":"Nowak-G\u00f6ttl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2008,8,19]]},"reference":[{"key":"S1047951100004741_ref006","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1055\/s-0038-1642714","article-title":"Developmental Hemostasis: Relevance of throm boembolic complications in pediatric patients","volume":"74","author":"Andrew","year":"1995","journal-title":"Thromb Haemost"},{"key":"S1047951100004741_ref005","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1055\/s-0038-1651110","article-title":"Laboratory screening of inheritated thrombotic syndromes","volume":"57","author":"Mannucci","year":"1987","journal-title":"Thromb Haemost"},{"key":"S1047951100004741_ref004","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1055\/s-0038-1642667","article-title":"New molecular insights into the genetics of thrombophilia. Resistance to activated protein C caused by Arg 506 to GIn mutation in factor V as a pathogenetic risk factor","volume":"74","author":"Dahlb\u00e4ck","year":"1995","journal-title":"Thromb Haemost"},{"key":"S1047951100004741_ref001","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5273(93)90008-5"},{"key":"S1047951100004741_ref002","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.3.1004"},{"key":"S1047951100004741_ref003","doi-asserted-by":"publisher","DOI":"10.1038\/369064a0"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951100004741","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T01:53:07Z","timestamp":1588902787000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951100004741\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,1]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1998,1]]}},"alternative-id":["S1047951100004741"],"URL":"https:\/\/doi.org\/10.1017\/s1047951100004741","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,1]]}}}