{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T23:00:30Z","timestamp":1788994830891,"version":"build-2803163510"},"reference-count":37,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2008,8,19]],"date-time":"2008-08-19T00:00:00Z","timestamp":1219104000000},"content-version":"unspecified","delay-in-days":3275,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[1999,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To judge whether an Amplatzer\u2122 Septal Occluder can be used as standard therapy instead of surgery for closure of atrial septal defects we report our experiences in 200 patients. Of these patients, 127 had an atrial septal defect with haemodynamically significant left-to-right shunt, 68 patients a persistent oval foramen after presumed paradoxical embolism, and 5 had a fenestration after Fontan-repair. Mean age was 29.8 years (0.8 to 77.7 years). Body weight ranged from 6.9 to 120.0 kg (mean 51.5 kg). After diagnostic cardiac catheterization, and balloon-sizing of the defect, we implanted Amplatzer\u2122 Septal Occluders with stents of 4 to 28 mm diameter. Follow-up studies were obtained after 48hours, and one, six, and twelve months. Transcatheter closure of the atrial septal defect proved successful in all without any relevant residual shunts. In particular, complete closure was achieved in all patients after presumed paradoxical embolism. The mean period of follow-up is 9\u20135 months, with a range from 0.4 to 23.5 months, giving a total of 1898 patient months. The occlusion rate after three month was 98.1\u00b0. A trivial haemodynamically insignificant residual shunt remained in 1.9\u00b0 of the patients. Fluoroscopy times ranged from 0 to 43.5 minutes, with a median of 8.7 minutes. The excellent results in the short and medium term in children and adults have resulted in using this device routinely at the present time for closure of central atrial septal defects up to a diameter of 28 mm. Final judgement, however, is only possible after long-term follow-up.<\/jats:p>","DOI":"10.1017\/s1047951100005369","type":"journal-article","created":{"date-parts":[[2008,8,31]],"date-time":"2008-08-31T20:06:53Z","timestamp":1220213213000},"page":"468-473","source":"Crossref","is-referenced-by-count":167,"title":["Transcatheter closure as standard treatment for most interatrial defects: experience in 200 patients treated with the Amplatzer \u2122 Septal Occluder"],"prefix":"10.1017","volume":"9","author":[{"given":"Felix","family":"Berger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Ewert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per G.","family":"Bo\u00f6jrnstad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingo","family":"D\u00e4hnert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregor","family":"Krings","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ira","family":"Brilla-Austenat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Vogel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter E.","family":"Lange","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2008,8,19]]},"reference":[{"key":"S1047951100005369_ref021","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.81.3.227"},{"key":"S1047951100005369_ref018","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.80.5.517"},{"key":"S1047951100005369_ref017","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(96)90366-X"},{"key":"S1047951100005369_ref013","first-page":"1117","article-title":"Transcatheter closure of atrial septal defect: are we there yet?","volume":"31","author":"Rao","year":"1998","journal-title":"J Am Coll Cardiol"},{"key":"S1047951100005369_ref012","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.160.1.8416621"},{"key":"S1047951100005369_ref010","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(92)90863-T"},{"key":"S1047951100005369_ref009","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.79.5.1091"},{"key":"S1047951100005369_ref006","first-page":"490","article-title":"Atrial septal defect in the adult: clinical course with medical treatment, pre-operative risk, and long-term postoperative survival","volume":"132","author":"Meisel","year":"1997","journal-title":"Harefuah"},{"key":"S1047951100005369_ref011","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.88.4.1754"},{"key":"S1047951100005369_ref004","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.61.1.29"},{"key":"S1047951100005369_ref037","first-page":"2961","article-title":"Catheter treatment of congenital heart defects. 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