{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T01:23:23Z","timestamp":1779326603063,"version":"3.51.4"},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"S1","license":[{"start":{"date-parts":[[2005,9,21]],"date-time":"2005-09-21T00:00:00Z","timestamp":1127260800000},"content-version":"unspecified","delay-in-days":598,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2004,2]]},"abstract":"<jats:p>In this Supplement, and at its associated Symposium \u201cControversies of Hypoplastic Left Heart Syndrome\u201d, various contributors presented a variety of topics regarding \u201cstate of the art\u201d treatments for hypoplastic left heart syndrome. The extent of the differences within these various presentations attests to the very significant challenges that remain in optimizing care of these patients, and related ones with other types of functionally univentricular hearts. Of these challenges, the initial surgical approach, be it staged palliation or cardiac transplantation, has been a hotly debated issue, with diametrically opposed schools of thought.<jats:sup>1<\/jats:sup>Today, with further experience, technical advances, and dramatically improved outcomes, there seems to be an emerging complimentary role for both options, favoring a staged reconstructive approach in the majority of circumstances. We review here the salient issues that have lead to this position, and discuss strategies for maintaining a program offering both staged palliation and transplantation for patients with hypoplasia of the left heart.<\/jats:p>","DOI":"10.1017\/s1047951104006456","type":"journal-article","created":{"date-parts":[[2005,9,21]],"date-time":"2005-09-21T12:00:30Z","timestamp":1127304030000},"page":"127-130","source":"Crossref","is-referenced-by-count":14,"title":["Achieving a balance in the current approach to the surgical treatment of hypoplastic left heart syndrome"],"prefix":"10.1017","volume":"14","author":[{"given":"James A.","family":"Quintessenza","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor O.","family":"Morell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey P.","family":"Jacobs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2005,9,21]]},"reference":[{"key":"S1047951104006456_ref005","doi-asserted-by":"crossref","unstructured":"Norwood WI , Lang P , Castaneda AR , Campbell DN . Experience with operations for hypoplastic left heart syndrome. J Thorac Cardiovasc Surg 1981; 82: 511\u2013519.","DOI":"10.1016\/S0022-5223(19)39288-8"},{"key":"S1047951104006456_ref006","doi-asserted-by":"crossref","unstructured":"Doty DB , Marvin WJ , Schieken RM , Lauer RM . Hypoplastic left heart syndrome. Successful palliation with a new operation. J Thorac Cardiovasc Surg 1980; 80: 148\u2013152.","DOI":"10.1016\/S0022-5223(19)37842-0"},{"key":"S1047951104006456_ref011","unstructured":"Norwood WI , Pizarro C . Presented at the 2002 Annual Congenital Heart Surgeons' Society Meeting, Chicago, Illinois, Monday, September 30, 2002."},{"key":"S1047951104006456_ref007","doi-asserted-by":"crossref","unstructured":"Fraser CD, Jr ., Mee RBB . Modified Norwood procedure for hypoplastic left heart syndrome. Ann Thorac Surg 1995; 60: S546\u2013S549.","DOI":"10.1016\/0003-4975(95)00848-9"},{"key":"S1047951104006456_ref013","unstructured":"Jacobs JP , Quintessenza JA , Boucek RJ , Morell VO , Botero LM , Badhwar V , van Gelder HM , Asante-Korang A , McCormack J , Daicoff GR . Pediatric Cardiac Transplantation in Children with High Panel Reactive Antibody. Ann Thorac Surg \u2013 in review."},{"key":"S1047951104006456_ref003","doi-asserted-by":"crossref","unstructured":"Bailey LL , Gundry SR , Razzouk AJ , Wang N , Sciolaro CM , Chiavarelli M . Bless the babies. J Thorac Cardiovasc Surg 1993; 105: 805\u2013815.","DOI":"10.1016\/S0022-5223(19)34154-6"},{"key":"S1047951104006456_ref009","unstructured":"Sano S , Ishino K , Kawada M , Fujisawa E , Kasahara S , Nakanishi K , Arai S , Hisamochi K , Kamada M , Ohtsuki S . The modified Norwood operation for hypoplastic left heart syndrome: using right ventricle-to-pulmonary artery shunt. Cardiol Young 2001; 11 (Suppl 1): 21."},{"key":"S1047951104006456_ref010","doi-asserted-by":"crossref","unstructured":"Sano S . Outcome of right ventricle-to-pulmonary artery shunt in first stage palliation of hypoplastic left heart syndrome \u2013 Multi Institutional Study. Presented at the 2003 Society of Thoracic Surgeons Meeting.","DOI":"10.1016\/j.athoracsur.2004.05.055"},{"key":"S1047951104006456_ref014","doi-asserted-by":"crossref","unstructured":"West LJ , Pollock-Barziv SM , Dipchand AI , Lee KJ , Cardella CJ , Benson LN , Rebeyka IM , Coles JG . ABO-incompatible heart transplantation in infants. N Engl J Med. 2001; 344: 793\u2013800.","DOI":"10.1056\/NEJM200103153441102"},{"key":"S1047951104006456_ref001","doi-asserted-by":"crossref","unstructured":"Jacobs ML , Blackstone EH , Bailey LL , and The Congenital Heart Surgeons Society. Intermediate survival in neonates with aortic atresia: a multi-institutional study. J Thorac Cardiovasc Surg 1998; 116: 417\u2013431.","DOI":"10.1016\/S0022-5223(98)70008-X"},{"key":"S1047951104006456_ref008","doi-asserted-by":"crossref","unstructured":"Bove EL , Lloyd TR . Staged reconstruction for hypoplastic left heart syndrome. Ann Surg 1996; 224: 387\u2013395.","DOI":"10.1097\/00000658-199609000-00015"},{"key":"S1047951104006456_ref004","doi-asserted-by":"crossref","unstructured":"Norwood WI , Kirklin JK , Sanders SP . Hypoplastic left heart syndrome. Experience with palliative surgery. Am J Cardiol 1980; 45: 87\u201391.","DOI":"10.1016\/0002-9149(80)90224-6"},{"key":"S1047951104006456_ref012","unstructured":"Jacobs JP , Quintessenza JA , Boucek RJ , Morell VO , Botero LM , Badhwar V , van Gelder HM , Asante-Korang A , McCormack J . Pediatric Cardiac Transplantation in Children with High Pre-Formed Reactive Antibody. In: Proceedings of the 50th Annual Meeting of The Southern Thoracic Surgical Association, Bonita Springs, Florida, Abstract 7, P 42, November 13\u201315, 2003."},{"key":"S1047951104006456_ref015","doi-asserted-by":"crossref","unstructured":"Checchia PA , Larsen R , Sehra R , Liu A , Daher N , Gundry S , Bailey L . The effect of a candidate selection scoring system and postoperative care protocol on survival following hypoplastic left heart syndrome palliation. Presented at the Society of Critical Care Medicine 32nd Critical Care Congress. January, 2003, San Antonio, Texas. Crit Care Med (Suppl) 2003; 31: A73.","DOI":"10.1097\/00003246-200212001-00251"},{"key":"S1047951104006456_ref002","doi-asserted-by":"crossref","unstructured":"Bailey LL , Nehlsen-Cannarella SL , Doroshow RW , et al. Cardiac allotransplantation in newborns as therapy for hypoplastic left heart syndrome. N Engl J Med 1986; 315: 949\u2013951.","DOI":"10.1056\/NEJM198610093151507"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951104006456","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,9]],"date-time":"2020-04-09T19:42:11Z","timestamp":1586461331000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951104006456\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,2]]},"references-count":15,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2004,2]]}},"alternative-id":["S1047951104006456"],"URL":"https:\/\/doi.org\/10.1017\/s1047951104006456","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,2]]}}}