{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T18:09:48Z","timestamp":1787508588569,"version":"build-2736575974"},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2005,4,14]],"date-time":"2005-04-14T00:00:00Z","timestamp":1113436800000},"content-version":"unspecified","delay-in-days":103,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:p>\n                    <jats:italic>Background:<\/jats:italic>\n                    Post-operative junctional ectopic tachycardia is a transient, but potentially life threatening, rapid automatic tachyarrhythmia that requires urgent and adequate treatment. In our study, we review retrospectively the use and efficacy of amiodarone for this arrhythmia over an 8-year period in our institution.\n                    <jats:italic>Methods and patients:<\/jats:italic>\n                    Retrospective review revealed 15 patients who were administered amiodarone for post-operative junctional ectopic tachycardia during the period. The median age was 2.6 months, with a range from 8 days to 8.1 months. The median weight was 4.6 kilograms, with a range from 2.6 to 8.2 kilograms.\n                    <jats:italic>Results:<\/jats:italic>\n                    The median heart rate at diagnosis of the tachycardia was 192 beats per minute, and the range was 182 to 229 beats per minute. The biochemistry was essentially normal. The median length of time until the tachycardia was controlled was 4.5 hours, and the range was from 1 to 19.5 hours, with 13 of the 15 patients controlled within 12 hours. The median dose of amiodarone received by this time was 5.9 milligrams per kilogram, with a range from 1.0 to 25.0 milligrams per kilogram. Hypotension or bradycardia within 4 hours of commencing amiodarone were noted in 2 patients.\n                    <jats:italic>Conclusion:<\/jats:italic>\n                    Experience in our institution, and a review of the literature, suggests that the most rapid control of post-operative junctional ectopic tachycardia will be obtained by a bolus of amiodarone followed by an intravenous infusion. Intravenous amiodarone is generally safe, with few side effects. Reported life threatening arrhythmias, however, suggest that intravenous amiodarone should be restricted to a setting where invasive monitoring and external cardiac pacing are available.\n                  <\/jats:p>","DOI":"10.1017\/s1047951105000041","type":"journal-article","created":{"date-parts":[[2005,4,14]],"date-time":"2005-04-14T10:25:05Z","timestamp":1113474305000},"page":"13-18","source":"Crossref","is-referenced-by-count":33,"title":["Amiodarone for post-operative junctional ectopic tachycardia"],"prefix":"10.1017","volume":"15","author":[{"given":"Kevin","family":"Plumpton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Justo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaus","family":"Haas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2005,4,14]]},"reference":[{"key":"S1047951105000041_ref001","doi-asserted-by":"crossref","unstructured":"Dodge-Khatami A , Miller OI , Anderson RH , Gil-Jaurena JM , Goldman AP , de Leval MR . Impact of junctional ectopic tachycardia on postoperative morbidity following repair of congenital heart defects. Eur J Cardiothorac Surg 2002; 21: 255\u2013259.","DOI":"10.1016\/S1010-7940(01)01089-2"},{"key":"S1047951105000041_ref006","unstructured":"Gandy J , Wonko N , Kantoch MJ . Risks of intravenous amiodarone in neonates. Can J Cardiol 1998; 14: 855\u2013858."},{"key":"S1047951105000041_ref009","doi-asserted-by":"crossref","unstructured":"Haas NA , Plumpton K , Justo R , Jalali H , Pohlner P . Postoperative junctional ectopic tachycardia (JET). Z Kardiol 2004; 93: 371\u2013380.","DOI":"10.1007\/s00392-004-0067-3"},{"key":"S1047951105000041_ref013","doi-asserted-by":"crossref","unstructured":"England MR , Gordon G , Salem M , Chernow B . Magnesium administration and dysrhythmias after cardiac surgery. A placebo-controlled, double-blind, randomized trial. 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Correction of ionized plasma magnesium during cardiopulmonary bypass reduces the risk of postoperative cardiac arrhythmia. Anesth Analg 2002; 95: 828\u2013834 (Table of Contents).","DOI":"10.1213\/00000539-200210000-00008"},{"key":"S1047951105000041_ref007","doi-asserted-by":"crossref","unstructured":"Celiker A , Ceviz N , Ozme S . Effectiveness and safety of intravenous amiodarone in drug-resistant tachyarrhythmias of children. Acta Paediatr Jpn 1998; 40: 567\u2013572.","DOI":"10.1111\/j.1442-200X.1998.tb01992.x"},{"key":"S1047951105000041_ref011","doi-asserted-by":"crossref","unstructured":"Walsh EP , Saul JP , Sholler GF , et al. Evaluation of a staged treatment protocol for rapid automatic junctional tachycardia after operation for congenital heart disease. J Am Coll Cardiol 1997; 29: 1046\u20131053.","DOI":"10.1016\/S0735-1097(97)00040-5"},{"key":"S1047951105000041_ref008","doi-asserted-by":"crossref","unstructured":"Yap SC , Hoomtje T , Sreeram N . Polymorphic ventricular tachycardia after use of intravenous amiodarone for postoperative junctional ectopic tachycardia. Int J Cardiol 2000; 76: 245\u2013247.","DOI":"10.1016\/S0167-5273(00)00388-0"},{"key":"S1047951105000041_ref012","unstructured":"MIMS online. Sydney, NSW: Hcn.; 2004."},{"key":"S1047951105000041_ref014","doi-asserted-by":"crossref","unstructured":"Fox ML , Burrows FA , Reid RW , Hickey PR , Laussen PC , Hansen DD . The influence of cardiopulmonary bypass on ionized magnesium in neonates, infants, and children undergoing repair of congenital heart lesions. Anesth Analg 1997; 84: 497\u2013500.","DOI":"10.1097\/00000539-199703000-00005"},{"key":"S1047951105000041_ref005","doi-asserted-by":"crossref","unstructured":"Laird WP , Snyder CS , Kertesz NJ , Friedman RA , Miller D , Fenrich AL . Use of intravenous amiodarone for postoperative junctional ectopic tachycardia in children. 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