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Postnatal options for treatment include comfort care, 3-stage palliative surgery, or cardiac transplantation. In this review, we discuss the morphology, possible pathogenetic mechanisms, clinical management, and perspectives of prenatal intervention based on work in animal models.<\/jats:p>","DOI":"10.1017\/s1047951105000132","type":"journal-article","created":{"date-parts":[[2005,4,14]],"date-time":"2005-04-14T14:25:05Z","timestamp":1113488705000},"page":"56-72","source":"Crossref","is-referenced-by-count":49,"title":["Current issues and perspectives in hypoplasia of the left heart"],"prefix":"10.1017","volume":"15","author":[{"given":"David","family":"Sedmera","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew C.","family":"Cook","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Girish","family":"Shirali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim C.","family":"McQuinn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2005,4,14]]},"reference":[{"key":"S1047951105000132_ref034","doi-asserted-by":"crossref","unstructured":"van Nie CJ , van Messel MA , Straatman TJ . 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