{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T16:10:40Z","timestamp":1772122240298,"version":"3.50.1"},"reference-count":26,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2009,8,1]],"date-time":"2009-08-01T00:00:00Z","timestamp":1249084800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2009,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1047951109990308_abs1\" sec-type=\"general\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>We report the experience in a single institution with balloon aortic valvoplasty for congenital aortic stenosis. Unlike most other reported series, we included patients with associated lesions involving the left side of the heart.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951109990308_abs2\" sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Between November, 1986, and November, 2006, we performed 161 interventions on 143 patients, of whom 33 were neonates, 33 infants, and 77 children, just over one-quarter (28.6%) having associated lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951109990308_abs3\" sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The overall reduction in peak-to-peak gradient of 60 \u00b1 24% (p &lt; 0.01), was more effective in primary versus secondary intervention (63 \u00b1 24% versus 47 \u00b1 23%; p &lt; 0.03), and in those with fused bifoliate as opposed to truly bifoliate valves (66 \u00b1 17% versus 53 \u00b1 30%; p = 0.01). Patients with associated lesions were younger (40.89 \u00b1 60.92 months versus 81.9 \u00b1 72.9 months; p = 0.001), and were less likely to achieve a final pressure gradient of less than 20 mmHg (35.0% versus 61.2%; p &lt; 0.01). Overall mortality was higher in cases with associated lesions (27.5% versus 1.9%; p &lt; 0.0001) but not catheter-related death (2.5% versus 1.9%; p = 1.0). Reintervention was more frequently required in infants (p = 0.02) but not in cases with associated lesions (p = 0.35).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951109990308_abs4\" sec-type=\"conclusion\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Balloon valvoplasty is a safe and effective method for the treatment of congenital aortic stenosis. Prior surgery to the aortic valve, reintervention, associated cardiovascular lesions, and the anatomy of the valve predict a less effective reduction in the gradient. Major complications and catheterization-related death are mainly secondary to very young age, but not to associated cardiac lesions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1047951109990308","type":"journal-article","created":{"date-parts":[[2009,6,11]],"date-time":"2009-06-11T08:41:02Z","timestamp":1244709662000},"page":"372-382","source":"Crossref","is-referenced-by-count":16,"title":["Experience in a single centre with percutaneous aortic valvoplasty in children, including those with associated cardiovascular lesions"],"prefix":"10.1017","volume":"19","author":[{"given":"David","family":"Crespo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joaquim","family":"Mir\u00f3","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne J","family":"Vobecky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy","family":"Poirier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chantal","family":"Lapierre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naicheng NZ","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nagib","family":"Dahdah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,8,1]]},"reference":[{"key":"S1047951109990308_ref5","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000153809.88286.2E"},{"key":"S1047951109990308_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(89)90269-6"},{"key":"S1047951109990308_ref21","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.687764"},{"key":"S1047951109990308_ref26","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.82.6.e10"},{"key":"S1047951109990308_ref18","doi-asserted-by":"publisher","DOI":"10.1136\/heart.90.1.70"},{"key":"S1047951109990308_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(97)00067-2"},{"key":"S1047951109990308_ref7","first-page":"48","article-title":"Percutaneous 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