{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T19:55:13Z","timestamp":1792180513284,"version":"4.4.0"},"reference-count":45,"publisher":"Cambridge University Press (CUP)","issue":"S3","license":[{"start":{"date-parts":[[2010,12,1]],"date-time":"2010-12-01T00:00:00Z","timestamp":1291161600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Anomalous origin of the left coronary artery from the pulmonary artery is a rare congenital cardiac malformation that accounts for 0.25\u20130.50% of children with congenital cardiac disease and can cause myocardial dysfunction in young infants. In any infant presenting with ventricular dysfunction, the diagnosis of anomalous origin of the left coronary artery from the pulmonary artery must be suspected and the origin of the coronary arteries must be confirmed. The diagnosis of anomalous origin of the left coronary artery from the pulmonary artery is an indication for surgical repair. A two-coronary arterial system is the goal and is almost always achievable. The goal of surgical therapy is the creation of a two-coronary arterial system, which appears to provide better long-term survival and protection from left ventricular dysfunction and mitral valvar regurgitation than does simple ligation of the anomalous coronary artery. Direct reimplantation of the anomalous coronary artery is the procedure of choice. It is straightforward and borrows from well-practised techniques commonly used in other procedures such as the arterial switch operation. For the rare patient in whom direct reimplantation is not possible, strategies to lengthen the anomalous coronary artery, or baffle it within the pulmonary root, are available. Mitral valvar regurgitation is common at presentation, but following the establishment of a two-coronary arterial system and satisfactory myocardial perfusion, regurgitation of the mitral valve resolves in the vast majority. Therefore, mitral valvuloplasty at the time of initial surgery for anomalous origin of the left coronary artery from the pulmonary artery is not indicated. Post-operative care requires careful manipulation of inotropic support and reduction of afterload. Mechanical support, with either extracorporeal membrane oxygenation or left ventricular assist device, should be available for use if necessary.<\/jats:p>","DOI":"10.1017\/s1047951110001071","type":"journal-article","created":{"date-parts":[[2011,7,20]],"date-time":"2011-07-20T08:11:16Z","timestamp":1311149476000},"page":"35-43","source":"Crossref","is-referenced-by-count":6,"title":["Surgery and critical care for anomalous coronary artery from the pulmonary artery"],"prefix":"10.1017","volume":"20","author":[{"given":"Timothy A.","family":"Fehrenbacher","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael E.","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy S.","family":"Ghanayem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James S.","family":"Tweddell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2010,12,1]]},"reference":[{"key":"S1047951110001071_ref32","first-page":"399","article-title":"Anomalous origin of the left coronary artery: a review of surgical management in 13 patients","volume":"34","author":"Wollenek","year":"1993","journal-title":"J Cardiovasc Surg (Torino)"},{"key":"S1047951110001071_ref39","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(95)70404-3"},{"key":"S1047951110001071_ref23","first-page":"433","volume-title":"Pediatric Surgery","author":"Mustard","year":"1962"},{"key":"S1047951110001071_ref37","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(03)00897-X"},{"key":"S1047951110001071_ref44","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2009.03.014"},{"key":"S1047951110001071_ref42","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199511000-00018"},{"key":"S1047951110001071_ref40","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.8.2226"},{"key":"S1047951110001071_ref41","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2002.120305"},{"key":"S1047951110001071_ref36","doi-asserted-by":"publisher","DOI":"10.1007\/978-4-431-99470-1"},{"key":"S1047951110001071_ref33","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(79)90248-5"},{"key":"S1047951110001071_ref29","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0022-5223(19)38154-1","article-title":"New surgical method for repair of anomalous left coronary artery from pulmonary artery","volume":"78","author":"Takeuchi","year":"1979","journal-title":"J Thorac Cardiovasc Surg"},{"key":"S1047951110001071_ref28","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.50.3.582"},{"key":"S1047951110001071_ref27","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/S0022-5223(19)42879-1","article-title":"A method of definitive surgical treatment of anomalous origin of left coronary artery. 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