{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T11:40:42Z","timestamp":1788522042157,"version":"build-2803163510"},"reference-count":11,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2010,10,27]],"date-time":"2010-10-27T00:00:00Z","timestamp":1288137600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2011,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951110001447_abs1\" sec-type=\"general\"><jats:title>Background<\/jats:title><jats:p>Patients with repaired tetralogy of Fallot may develop symptomatic and haemodynamic deterioration for many reasons such as arrhythmia, pulmonary regurgitation, and impairment in ventricular function. We describe a consecutive group of patients whose main clinical problem was atrial tachyarrhythmias.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951110001447_abs2\" sec-type=\"general\"><jats:title>Aims<\/jats:title><jats:p>To describe the clinical outcome of atrial tachyarrhythmias occurring late after surgical repair of tetralogy of Fallot; to define the circuits\/foci responsible for these atrial tachyarrhythmias; to evaluate the outcome of computer-assisted mapping and catheter ablation in this patient group.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951110001447_abs3\" sec-type=\"general\"><jats:title>Methods and results<\/jats:title><jats:p>Consecutive patients with surgically repaired tetralogy of Fallot and atrial tachyarrhythmias, who underwent catheter ablation between January, 2001 and June, 2007, were identified retrospectively from case records. Computer-assisted mapping was performed in all using either EnSite<jats:sup>\u00ae<\/jats:sup> (St Jude Medical Inc.) arrhythmia mapping and intra-cardiac catheter guidance system or CARTO\u2122 (Biosense Webster Inc.) electroanatomical mapping systems. Ten patients (four males) with a median age of 39 plus or minus 8 years were studied. The total number of atrial tachyarrhythmias identified was 22 (six macro-reentrant, 16 micro-reentrant\/focal). In nine patients, catheter ablation led to improvement in arrhythmia episodes and\/or symptoms during follow-up of 41 plus or minus 20 months. Following ablation(s), five patients required pacing for pre-existing conduction disease and five needed further surgery for haemodynamic indications. All patients remained on anti-arrhythmic drugs.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951110001447_abs4\" sec-type=\"conclusion\"><jats:title>Conclusions<\/jats:title><jats:p>Patients with surgically repaired tetralogy of Fallot and atrial tachyarrhythmias typically have multiple arrhythmic circuits\/foci arising from a scarred right atrium. Catheter ablation reduces arrhythmia frequency and improves symptoms. However, hybrid management is often required, comprising drugs, pacing, and further surgery tailored to the individual.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951110001447","type":"journal-article","created":{"date-parts":[[2010,10,27]],"date-time":"2010-10-27T09:22:42Z","timestamp":1288171362000},"page":"31-38","source":"Crossref","is-referenced-by-count":5,"title":["Ablation of atrial tachyarrhythmias late after surgical repair of tetralogy of Fallot"],"prefix":"10.1017","volume":"21","author":[{"given":"Dan","family":"Raine","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"O\u2019Sullivan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milind","family":"Chaudhari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie","family":"Hamilton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asif","family":"Hasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Bourke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2010,10,27]]},"reference":[{"key":"S1047951110001447_ref6","first-page":"1035","article-title":"Arrhythmias after surgery for congenital heart disease","volume":"95","author":"Lucet","year":"2002","journal-title":"Arch Mal Coeur Vaiss"},{"key":"S1047951110001447_ref7","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-08-0194"},{"key":"S1047951110001447_ref9","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.2002.3168"},{"key":"S1047951110001447_ref1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.91.8.2214"},{"key":"S1047951110001447_ref11","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.5.699"},{"key":"S1047951110001447_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/1010-7940(94)90114-7"},{"key":"S1047951110001447_ref10","first-page":"268","article-title":"Ablation of atrial tachycardias with radiofrequency current after surgical repair of complex congenital heart defects","volume":"48","author":"Papagiannis","year":"2007","journal-title":"Hellenic J Cardiol"},{"key":"S1047951110001447_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(03)00469-7"},{"key":"S1047951110001447_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2005.12.039"},{"key":"S1047951110001447_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02714-8"},{"key":"S1047951110001447_ref5","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2001.111765"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951110001447","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,27]],"date-time":"2019-04-27T19:37:09Z","timestamp":1556393829000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951110001447\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10,27]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["S1047951110001447"],"URL":"https:\/\/doi.org\/10.1017\/s1047951110001447","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,10,27]]}}}