{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T23:06:24Z","timestamp":1786748784178,"version":"build-2736575974"},"reference-count":12,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2012,3,8]],"date-time":"2012-03-08T00:00:00Z","timestamp":1331164800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951112000200_abs1\" sec-type=\"general\"><jats:title>Aim<\/jats:title><jats:p>Women with congenital heart disease are often considered to be restricted in their obstetrical life and even their marital life. Our single-centre study aimed to determine the real-life situation of these women with regard to successful family life and any pregnancy complications they may experience.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951112000200_abs2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>From our database of adults with congenital heart disease, 160 of 178 women completed a questionnaire and had their files reviewed. They were classified into three groups according to their pregnancy risk \u2013 \u201cgood condition\u201d group, no pregnancy restriction; \u201cat-risk\u201d group, pregnancy allowed with close follow-up at a tertiary centre; and \u201ccontraindicated\u201d group, pregnancy inadvisable.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951112000200_abs3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>The proportion of women in a relationship was 46% with no difference between the three groups. In the groups where pregnancy was allowed, 55% of women conceived a child. The total incidence of spontaneous abortion was 21%. The rate of caesarean section was 15%. The incidence of cardiac failure was 4.7%, arrhythmia 1.2%, endocarditis 1.2%, hypertension 2.4%, and preeclampsia 1.2%. Foetal complications included prematurity and\/or low birth weight (9.5%) and one foetal malformation (0.82%).<\/jats:p><\/jats:sec><jats:sec id=\"S1047951112000200_abs4\" sec-type=\"conclusion\"><jats:title>Conclusion<\/jats:title><jats:p>Women with severe congenital heart disease are willing to start a family and are successful in this enterprise. Although the complication rate during pregnancy in congenital heart disease remains high, with good monitoring these pregnancies occur without severe complications and a low rate of medical abortion or caesarean section.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951112000200","type":"journal-article","created":{"date-parts":[[2012,3,8]],"date-time":"2012-03-08T06:23:17Z","timestamp":1331187797000},"page":"41-46","source":"Crossref","is-referenced-by-count":5,"title":["Does congenital heart disease severely jeopardise family life and pregnancies? Obstetrical history of women with congenital heart disease in a single tertiary centre"],"prefix":"10.1017","volume":"23","author":[{"given":"Marielle","family":"Morissens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Viart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Tecco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Wauthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Michiels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugues","family":"Dessy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Malekzadeh Milani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Verbeet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Castro Rodriguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2012,3,8]]},"reference":[{"key":"S1047951112000200_ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-003-0880-0"},{"key":"S1047951112000200_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2010.05.045"},{"key":"S1047951112000200_ref12","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.89.6.2673"},{"key":"S1047951112000200_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(12)62387-8"},{"key":"S1047951112000200_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2007.10.030"},{"key":"S1047951112000200_ref8","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000015699.48605.08"},{"key":"S1047951112000200_ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2009.01029.x"},{"key":"S1047951112000200_ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2009.02301.x"},{"key":"S1047951112000200_ref10","doi-asserted-by":"publisher","DOI":"10.1161\/hc3001.093437"},{"key":"S1047951112000200_ref6","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq200"},{"key":"S1047951112000200_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.03.027"},{"key":"S1047951112000200_ref1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.589655"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951112000200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,24]],"date-time":"2019-04-24T15:46:22Z","timestamp":1556120782000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951112000200\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,8]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["S1047951112000200"],"URL":"https:\/\/doi.org\/10.1017\/s1047951112000200","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3,8]]}}}