{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,14]],"date-time":"2026-11-14T08:25:15Z","timestamp":1794644715685,"version":"4.9.1"},"reference-count":27,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2012,3,15]],"date-time":"2012-03-15T00:00:00Z","timestamp":1331769600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951112000224_abs1\" sec-type=\"general\"><jats:title>Objectives<\/jats:title><jats:p>To assess clinical presentation, treatment, and outcome of children with Ebstein's anomaly.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951112000224_abs2\" sec-type=\"general\"><jats:title>Background<\/jats:title><jats:p>Data on long-term outcome of children with Ebstein's anomaly are scarce.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951112000224_abs3\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>Retrospective analysis of all children with Ebstein's anomaly treated between February, 1979 and January, 2009 in a single tertiary institution. Primary outcomes included patient survival and need for intervention, either cardiac surgery or catheter intervention.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951112000224_abs4\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>A total of 42 patients were diagnosed with Ebstein's anomaly at a median age of 5 days ranging from 1 day to 11.7 years. Symptoms included cyanosis, heart murmur, and\/or dyspnoea. Associated cardiac anomalies occurred in 90% of the patients. Average follow-up was 9.5 plus or minus 7.0 years. The overall mortality rate was 14%. Of the six patients, three died postnatally before treatment. Cardiac surgery and\/or catheter-guided interventions were required in 33 patients (79%). Cardiac surgery was performed in 21 (50%) patients at a median age of 9.1 years (range 0.1\u201316.5 years), including biventricular repair in 13 (62%), one-and-a-half chamber repair in seven (33%), and a staged single-ventricle repair in one. Peri-operative mortality was 4%. Catheter-guided interventions consisted of device closure of an atrial septal defect in three cases and radiofrequency ablation of accessory pathways in nine patients. The estimated 10-year survival was 85.3 plus or minus 5.6%.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951112000224_abs5\" sec-type=\"conclusion\"><jats:title>Conclusion<\/jats:title><jats:p>In children, Ebstein's anomaly is usually diagnosed in the first year of age. Even though children with Ebstein's anomaly often require an intervention, their peri-operative mortality is low and long-term survival is good. Symptomatic newborns requiring an intervention may have a worse outcome.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951112000224","type":"journal-article","created":{"date-parts":[[2012,3,15]],"date-time":"2012-03-15T12:47:45Z","timestamp":1331815665000},"page":"27-34","source":"Crossref","is-referenced-by-count":19,"title":["Management and outcome of Ebstein's anomaly in children"],"prefix":"10.1017","volume":"23","author":[{"given":"Angela","family":"Oxenius","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine H.","family":"Attenhofer Jost","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9","family":"Pr\u00eatre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitendu","family":"Dave","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urs","family":"Bauersfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Kretschmar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burkhardt","family":"Seifert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Balmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuela R.","family":"Valsangiacomo Buechel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2012,3,15]]},"reference":[{"key":"S1047951112000224_ref6","first-page":"185","article-title":"Surgical repair of Ebstein's anomaly","volume":"54","author":"Danielson","year":"1979","journal-title":"Mayo Clin Proc"},{"key":"S1047951112000224_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2004.02.013"},{"key":"S1047951112000224_ref5","first-page":"269","article-title":"Ebstein's anomaly \u2013 review of a multifaceted congenital cardiac condition","volume":"135","author":"Attenhofer Jost","year":"2005","journal-title":"Swiss Med Wkly"},{"key":"S1047951112000224_ref21","doi-asserted-by":"publisher","DOI":"10.1053\/j.pcsu.2007.01.008"},{"key":"S1047951112000224_ref26","doi-asserted-by":"publisher","DOI":"10.1016\/S1092-9126(03)70009-X"},{"key":"S1047951112000224_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90291-T"},{"key":"S1047951112000224_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.03.064"},{"key":"S1047951112000224_ref23","doi-asserted-by":"publisher","DOI":"10.1055\/s-2000-6897"},{"key":"S1047951112000224_ref13","doi-asserted-by":"publisher","DOI":"10.1053\/j.pcsu.2009.01.023"},{"key":"S1047951112000224_ref7","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/S0022-5223(19)35302-4","article-title":"A new reconstructive operation for Ebstein's anomaly of the tricuspid valve","volume":"96","author":"Carpentier","year":"1988","journal-title":"J Thorac Cardiovasc Surg"},{"key":"S1047951112000224_ref14","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20245"},{"key":"S1047951112000224_ref1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.619338"},{"key":"S1047951112000224_ref18","doi-asserted-by":"publisher","DOI":"10.2459\/JCM.0b013e3282f21654"},{"key":"S1047951112000224_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2007.08.019"},{"key":"S1047951112000224_ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2005.10.062"},{"key":"S1047951112000224_ref27","doi-asserted-by":"publisher","DOI":"10.1007\/BF02469380"},{"key":"S1047951112000224_ref15","first-page":"306","article-title":"Percutaneous closure of patent foramen ovale with amplatzer device. 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