{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T19:19:25Z","timestamp":1761765565495},"reference-count":32,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2012,6,14]],"date-time":"2012-06-14T00:00:00Z","timestamp":1339632000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951112000790_abs1\" sec-type=\"general\"><jats:title>Background<\/jats:title><jats:p>Patients with a congenitally corrected transposition of the great arteries show an increasing incidence of cardiac failure with age. In other systemic right ventricles, such as in dextro-transposition after atrial switch, excessive hypertrophy is a potential risk factor for impaired systolic function. In this trial, we sought to compare systemic function and volumes between patients with congenitally corrected transposition and those with dextro-transposition after atrial switch by using cardiac magnetic resonance imaging.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951112000790_abs2\" sec-type=\"general\"><jats:title>Methods and Results<\/jats:title><jats:p>A total of 19 patients (nine male) with congenitally corrected transposition and 31 patients (21 male) with dextro-transposition after atrial switch were studied using a 1.5-Tesla scanner. Cine steady-state free-precession sequences in standard orientations were acquired for volumetric and functional imaging. Patient parameters were compared with those of a group of 25 healthy volunteers. Although patients with congenitally corrected transposition were older, they presented with higher right ventricular ejection fractions (p = 0.04) compared with patients with dextro-transposition. Patients with congenitally corrected transposition showed a weak negative correlation between age at examination and systemic ejection fraction (r = \u22120.18, p = 0.04) but no correlation between right ventricular myocardial mass index and ejection fraction. There was no significant difference in the right ventricular end-diastolic volumes between both patient groups.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951112000790_abs3\" sec-type=\"conclusion\"><jats:title>Conclusion<\/jats:title><jats:p>Although patients with congenitally corrected transposition had a longer pressure load of the systemic right ventricle, ventricular function was better compared with that in patients with dextro-transposition after atrial switch. The results suggest that the systemic ventricles might have partly different physiologies. One difference could be the post-operative situation after atrial switch, which results in impaired atrial contribution to ventricular filling.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951112000790","type":"journal-article","created":{"date-parts":[[2012,6,14]],"date-time":"2012-06-14T08:57:54Z","timestamp":1339664274000},"page":"239-247","source":"Crossref","is-referenced-by-count":15,"title":["The systemic right ventricle in congenitally corrected transposition of the great arteries is different from the right ventricle in dextro-transposition after atrial switch: a cardiac magnetic resonance study"],"prefix":"10.1017","volume":"23","author":[{"given":"Matthias","family":"Grothoff","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antje","family":"Fleischer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hashim","family":"Abdul-Khaliq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janine","family":"Hoffmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lukas","family":"Lehmkuhl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Luecke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Gutberlet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2012,6,14]]},"reference":[{"key":"S1047951112000790_ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s00117-010-1996-7"},{"key":"S1047951112000790_ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-010-0252-5"},{"key":"S1047951112000790_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(98)70035-3"},{"key":"S1047951112000790_ref17","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-10-40"},{"key":"S1047951112000790_ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-006-0440-5"},{"key":"S1047951112000790_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(98)00913-8"},{"key":"S1047951112000790_ref32","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.10223"},{"key":"S1047951112000790_ref10","doi-asserted-by":"publisher","DOI":"10.1136\/heart.89.10.1231"},{"key":"S1047951112000790_ref23","doi-asserted-by":"publisher","DOI":"10.1007\/s11936-000-0045-7"},{"key":"S1047951112000790_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)00567-6"},{"key":"S1047951112000790_ref27","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(86)90070-6"},{"key":"S1047951112000790_ref25","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000162463.61626.3B"},{"key":"S1047951112000790_ref29","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.80.4.322"},{"key":"S1047951112000790_ref2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.74.1.57"},{"key":"S1047951112000790_ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-001-0037-8"},{"key":"S1047951112000790_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(02)02619-X"},{"key":"S1047951112000790_ref20","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.592352"},{"key":"S1047951112000790_ref15","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21948"},{"key":"S1047951112000790_ref26","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951105000326"},{"key":"S1047951112000790_ref22","doi-asserted-by":"publisher","DOI":"10.1203\/pdr.0b013e31805365a6"},{"key":"S1047951112000790_ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.05.062"},{"key":"S1047951112000790_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(89)90268-8"},{"key":"S1047951112000790_ref24","doi-asserted-by":"publisher","DOI":"10.1023\/A:1010692807154"},{"key":"S1047951112000790_ref31","doi-asserted-by":"publisher","DOI":"10.1016\/j.hfc.2008.02.007"},{"key":"S1047951112000790_ref18","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1056\/NEJM198710223171717","article-title":"Simplified calculation of body-surface area","volume":"317","author":"Mosteller","year":"1987","journal-title":"N Engl J Med"},{"key":"S1047951112000790_ref8","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.10.997"},{"key":"S1047951112000790_ref13","first-page":"942","article-title":"[Evaluation of left ventricular volumes in patients with congenital heart disease and abnormal left ventricular geometry. 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