{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T20:38:33Z","timestamp":1762979913062},"reference-count":36,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2012,7,20]],"date-time":"2012-07-20T00:00:00Z","timestamp":1342742400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951112000959_abs1\" sec-type=\"general\"><jats:title>Objectives<\/jats:title><jats:p>To describe our experience in the management of coronary artery anomalies both in an adult and in a paediatric population and to compare the two groups for finding out differences in terms of angiographic incidence and treatment.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951112000959_abs2\" sec-type=\"general\"><jats:title>Patients and methods<\/jats:title><jats:p>Databases at the Department of Cardiology of San Martino Adult's Hospital and of Gaslini Children's Hospital were searched for all patients with a diagnosis of coronary artery anomaly who underwent coronary angiography between 1994 and 2006.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951112000959_abs3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Coronary anomalies were diagnosed in 76 (1%) adult patients. Anomalous left circumflex artery was the commonest coronary anomaly (25%). Anomalous left coronary artery from pulmonary artery and myocardial bridges were the only anomalies responsible for angina-like symptoms. No patients except the one with anomalous left coronary artery from pulmonary artery needed surgical intervention. In the paediatric population, we found 28 (0.9%) patients with coronary anomalies. Anomalous left coronary artery from pulmonary artery was the most common anomaly (48%) and always required emergency surgical treatment; in addition there were two patients with stenosis of the left main coronary artery.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951112000959_abs4\" sec-type=\"conclusion\"><jats:title>Conclusion<\/jats:title><jats:p>Coronary artery anomalies may be associated with very acute, even life-threatening symptoms in children, whereas they are usually clinically silent and detected by accident on coronary angiography in adults. Recognition of coronary artery anomalies enables early treatment or close follow-up in children, whereas it could be useful in case of cardiac surgery in adults.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951112000959","type":"journal-article","created":{"date-parts":[[2012,7,20]],"date-time":"2012-07-20T23:50:22Z","timestamp":1342828222000},"page":"381-386","source":"Crossref","is-referenced-by-count":33,"title":["Incidence and clinical relevance of primary congenital anomalies of the coronary arteries in children and adults"],"prefix":"10.1017","volume":"23","author":[{"given":"Giulia","family":"Tuo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio","family":"Marasini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Brunelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucio","family":"Zannini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manrico","family":"Balbi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2012,7,20]]},"reference":[{"key":"S1047951112000959_ref10","first-page":"305","article-title":"Anomalous right or left coronary artery from the contralateral sinus: \u201chigh risk\u201d abnormalities in the initial coronary course and heterogenous clinical outcomes","volume":"4","author":"Taylor","year":"2003","journal-title":"Ital Heart J"},{"key":"S1047951112000959_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(85)90154-7"},{"key":"S1047951112000959_ref24","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.38.2.403"},{"key":"S1047951112000959_ref36","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.47.1.62"},{"key":"S1047951112000959_ref27","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5273(96)02792-1"},{"key":"S1047951112000959_ref34","doi-asserted-by":"publisher","DOI":"10.1177\/000331970405500105"},{"key":"S1047951112000959_ref11","first-page":"271","article-title":"Coronary artery anomalies \u2013 current clinical issues. 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