{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T20:13:37Z","timestamp":1769631217955,"version":"3.49.0"},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2012,9,20]],"date-time":"2012-09-20T00:00:00Z","timestamp":1348099200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951112001278_abs1\" sec-type=\"general\"><jats:title>Objective<\/jats:title><jats:p>We sought to describe the evaluation, treatment, and follow-up of adolescents who presented to a single institution with chest pain and an elevated troponin I value in the absence of typical symptoms of pericarditis or myocarditis.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951112001278_abs2\" sec-type=\"materialsandmethods\"><jats:title>Materials and methods<\/jats:title><jats:p>We performed a retrospective review of patients in the age group of 10\u201318 years of age with no history of significant heart disease admitted to our institution from 2000 to 2010 after presenting with chest pain and an elevated troponin I value.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951112001278_abs3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>A total of 16 patients were identified with a median age of 16.5 years (range 11.2\u201317.8 years). Of these 13 (81%) were male and 10 (63%) showed evidence of localised ST elevations on electrocardiogram. The median peak troponin I level was 17.8 nanograms per millilitre (range 0.89\u2013227, normal less than 0.4). There were eight patients (50%) with a diagnosis of coronary vasospasm, three patients (20%) with atypical myopericarditis, one patient with coronary anomaly, one patient with hypercoagulable disorder, and one patient with prolonged supraventricular tachycardia. In two patients, no definitive diagnosis was made. There was one patient who needed catheter-based intervention, which involved stenting of a coronary artery after a procedure-related complication.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951112001278_abs4\" sec-type=\"conclusion\"><jats:title>Conclusions<\/jats:title><jats:p>In our cohort of adolescents without history of significant cardiac disease, chest pain and elevated troponin I levels were attributed to a variety of causes. Although coronary vasospasm and atypical myopericarditis were seen most commonly, coronary anomaly was identified in one case. Magnetic resonance imaging proved a useful diagnostic tool to assess coronary artery anatomy and myocardial changes suggestive of myocarditis. On the basis of these results and a review of the literature, a general evaluation algorithm is presented.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951112001278","type":"journal-article","created":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T11:06:11Z","timestamp":1351767971000},"page":"353-360","source":"Crossref","is-referenced-by-count":12,"title":["Chest pain with elevated troponin assay in adolescents"],"prefix":"10.1017","volume":"23","author":[{"given":"Matthew C.","family":"Schwartz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shari","family":"Wellen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan J.","family":"Rome","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chitra","family":"Ravishankar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shobha","family":"Natarajan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2012,9,20]]},"reference":[{"key":"S1047951112001278_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(84)90298-4"},{"key":"S1047951112001278_ref5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0800028"},{"key":"S1047951112001278_ref1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0803.2010.00436.x"},{"key":"S1047951112001278_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(92)90700-9"},{"key":"S1047951112001278_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(86)80928-3"},{"key":"S1047951112001278_ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-004-0864-5"},{"key":"S1047951112001278_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2007.06.021"},{"key":"S1047951112001278_ref9","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.498006"},{"key":"S1047951112001278_ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.02.007"},{"key":"S1047951112001278_ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-011-9879-1"},{"key":"S1047951112001278_ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-011-0149-8"},{"key":"S1047951112001278_ref14","doi-asserted-by":"publisher","DOI":"10.1089\/cap.2005.15.693"},{"key":"S1047951112001278_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2011.11.002"},{"key":"S1047951112001278_ref7","unstructured":"Cannon CP, Braunwald E. Unstable angina and non ST elevation myocardial infarction. In: Bonow RO, Mann DL, Zipes DP, Libby P (eds.). Bonow: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 9th edn. Elsevier Saunders, Philadelphia, 2011, 1178\u20131209."},{"key":"S1047951112001278_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-0736(80)80011-2"},{"key":"S1047951112001278_ref6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp041997"},{"key":"S1047951112001278_ref11","doi-asserted-by":"publisher","DOI":"10.1378\/chest.107.5.1426"},{"key":"S1047951112001278_ref3","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-3123"},{"key":"S1047951112001278_ref8","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.187397"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951112001278","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,23]],"date-time":"2019-04-23T17:46:49Z","timestamp":1556041609000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951112001278\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,20]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["S1047951112001278"],"URL":"https:\/\/doi.org\/10.1017\/s1047951112001278","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,20]]}}}