{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T13:57:35Z","timestamp":1766066255231},"reference-count":22,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2013,2,8]],"date-time":"2013-02-08T00:00:00Z","timestamp":1360281600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951113000024_abs1\" sec-type=\"general\"><jats:title>Aim<\/jats:title><jats:p>To analyse the current practice and contribution of catheter interventions in the staged management of patients with hypoplastic left heart syndrome.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951113000024_abs2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>This study is a retrospective case note review of 527 patients undergoing staged Norwood\/Fontan palliation at a single centre between 1993 and 2010. Indications and type of catheter interventions were reviewed over a median follow-up period of 7.5 years.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951113000024_abs3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>A staged Norwood\/Fontan palliation for hypoplastic left heart syndrome was performed in 527 patients. The 30-day survival rate after individual stages was 76.5% at Stage I, 96.3% at Stage II, and 99.4% at Stage III. A total of 348 interventions were performed in 189 out of 527 patients. Freedom from catheter intervention in survivors was 58.2% before Stage II and 46.7% before Stage III. Kaplan\u2013Meier freedom from intervention post Fontan completion was 55% at 10.8 years of follow-up. Post-stage I interventions were mostly directed to relieve aortic arch obstruction \u2013 84 balloon angioplasties \u2013 and augment pulmonary blood flow \u2013 15 right ventricle-to-pulmonary conduit interventions; post-Stage II interventions centred on augmenting size of the left pulmonary artery \u2013 73 procedures and abolishing systemic venous collaterals \u2013 32 procedures. After Stage III, the focus was on manipulating the size of the fenestration \u2013 42 interventions \u2013 and the left pulmonary artery \u221231 procedures.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951113000024_abs4\" sec-type=\"conclusion\"><jats:title>Conclusion<\/jats:title><jats:p>Interventional cardiac catheterisation constitutes an integral part in the staged palliative management of patients with hypoplastic left heart syndrome. Over one-third (37%) of patients undergoing staged palliation required catheter intervention over the follow-up period.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951113000024","type":"journal-article","created":{"date-parts":[[2013,2,8]],"date-time":"2013-02-08T13:06:17Z","timestamp":1360328777000},"page":"212-219","source":"Crossref","is-referenced-by-count":15,"title":["Catheter interventions in the staged management of hypoplastic left heart syndrome"],"prefix":"10.1017","volume":"24","author":[{"given":"Zdenka","family":"Reinhardt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"De Giovanni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Stickley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vinay K.","family":"Bhole","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bari","family":"Murtuza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chetan","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Miller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rami","family":"Dhillon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Stumper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2013,2,8]]},"reference":[{"key":"S1047951113000024_ref5","doi-asserted-by":"publisher","DOI":"10.1136\/heart.89.10.1227"},{"key":"S1047951113000024_ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s12471-011-0171-8"},{"key":"S1047951113000024_ref22","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.1091"},{"key":"S1047951113000024_ref6","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.22661"},{"key":"S1047951113000024_ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-008-9283-3"},{"key":"S1047951113000024_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2009.05.004"},{"key":"S1047951113000024_ref9","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-1592"},{"key":"S1047951113000024_ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-007-0545-5"},{"key":"S1047951113000024_ref21","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.79.4.368"},{"key":"S1047951113000024_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(92)90065-C"},{"key":"S1047951113000024_ref12","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2000.108238"},{"key":"S1047951113000024_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(99)00782-1"},{"key":"S1047951113000024_ref14","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-726X(200005)50:1<54::AID-CCD11>3.0.CO;2-9"},{"key":"S1047951113000024_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(02)73575-7"},{"key":"S1047951113000024_ref15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0803.2009.00347.x"},{"key":"S1047951113000024_ref8","doi-asserted-by":"crossref","first-page":"I82","DOI":"10.1161\/01.cir.0000032878.55215.bd","article-title":"Improved survival of patients undergoing palliation of hypoplastic left heart syndrome: lessons learned from 115 consecutive patients","volume":"106","author":"Tweddell","year":"2002","journal-title":"Circulation"},{"key":"S1047951113000024_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.01.056"},{"key":"S1047951113000024_ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-004-0955-3"},{"key":"S1047951113000024_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00223-4"},{"key":"S1047951113000024_ref20","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.22667"},{"key":"S1047951113000024_ref7","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.068684"},{"key":"S1047951113000024_ref2","first-page":"41","article-title":"New developments in the treatment of hypoplastic left heart syndrome","volume":"56","author":"Maher","year":"2004","journal-title":"Minerva Pediatr"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951113000024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,29]],"date-time":"2023-06-29T09:59:56Z","timestamp":1688032796000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951113000024\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,8]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["S1047951113000024"],"URL":"https:\/\/doi.org\/10.1017\/s1047951113000024","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,8]]}}}