{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:10:54Z","timestamp":1761844254660},"reference-count":40,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2013,2,7]],"date-time":"2013-02-07T00:00:00Z","timestamp":1360195200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S104795111300005X_abs1\" sec-type=\"general\"><jats:title>Aims<\/jats:title><jats:p>To evaluate the role of torsion in hypertrophic cardiomyopathy in children.<\/jats:p><\/jats:sec><jats:sec id=\"S104795111300005X_abs2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>A total of 88 children with idiopathic hypertrophic cardiomyopathy (n = 24) and concentric hypertrophy (n = 20) were investigated with speckle-tracking echocardiography and compared with age- and gender-matched healthy controls (n = 44).<\/jats:p><\/jats:sec><jats:sec id=\"S104795111300005X_abs3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>In hypertrophic cardiomyopathy, we found increased torsion (2.8 \u00b1 1.6 versus 1.9 \u00b1 1.0\u00b0\/cm [controls], p &lt; 0.05) because of an increase in clockwise basal rotation (\u22128.7 \u00b1 4.3\u00b0 versus \u22124.9 \u00b1 2.5\u00b0 [controls], p &lt; 0.001) and prolonged time to peak diastolic untwisting (3.7 \u00b1 2.4% versus 1.7 \u00b1 0.6% [controls] of cardiac cycle, p &lt; 0.01), but no differences in peak untwisting velocities. Hypertrophic cardiomyopathy patients demonstrated a negative correlation between left ventricular muscle mass and torsion (r = \u22120.7, p &lt; 0.001). In concentric hypertrophy, torsion was elevated because of increased apical rotation (15.1 \u00b1 6.4\u00b0 versus 10.5 \u00b1 5.5\u00b0 [controls], p &lt; 0.05) without correlation with muscle mass. Peak untwisting velocities (\u2212 202 \u00b1 88 versus \u2212145 \u00b1 67\u00b0\/s [controls], p &lt; 0.05) were higher in concentric hypertrophy and time to peak diastolic untwisting was delayed (1.8 \u00b1 0.8% versus 1.2 \u00b1 0.6% [controls], p &lt; 0.05).<\/jats:p><\/jats:sec><jats:sec id=\"S104795111300005X_abs4\" sec-type=\"conclusion\"><jats:title>Conclusions<\/jats:title><jats:p>In contrast to an increased counterclockwise apical rotation in concentric hypertrophy, hypertrophic cardiomyopathy is characterised by predominantly enhanced systolic basal clockwise rotation. Diastolic untwisting is delayed in both groups. Torsion may be an interesting marker to guide patients with hypertrophic cardiomyopathy.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s104795111300005x","type":"journal-article","created":{"date-parts":[[2013,2,6]],"date-time":"2013-02-06T15:30:13Z","timestamp":1360164613000},"page":"245-252","source":"Crossref","is-referenced-by-count":7,"title":["Evaluation of left ventricular torsion in children with hypertrophic cardiomyopathy"],"prefix":"10.1017","volume":"24","author":[{"given":"Christian","family":"Prinz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lothar","family":"Faber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dieter","family":"Horstkotte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hermann","family":"K\u00f6rperich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Moysich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolaus","family":"Haas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deniz","family":"Kececioglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai","family":"Thorsten Laser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2013,2,7]]},"reference":[{"key":"S104795111300005X_ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2009.07.021"},{"key":"S104795111300005X_ref38","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.12.032"},{"key":"S104795111300005X_ref39","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2006.110460"},{"key":"S104795111300005X_ref31","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.178.4.1780953"},{"key":"S104795111300005X_ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2006.03.011"},{"key":"S104795111300005X_ref2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.81.4.1236"},{"key":"S104795111300005X_ref13","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2008.152777"},{"key":"S104795111300005X_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2008.02.001"},{"key":"S104795111300005X_ref32","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm444"},{"key":"S104795111300005X_ref30","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2009.06.014"},{"key":"S104795111300005X_ref7","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.706770"},{"key":"S104795111300005X_ref25","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.26.3.325"},{"key":"S104795111300005X_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)01282-8"},{"key":"S104795111300005X_ref35","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2010.01234.x"},{"key":"S104795111300005X_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.11.053"},{"key":"S104795111300005X_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(86)90771-X"},{"key":"S104795111300005X_ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2006.07.007"},{"key":"S104795111300005X_ref18","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.26.3.325"},{"key":"S104795111300005X_ref26","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.2.254"},{"key":"S104795111300005X_ref14","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jep151"},{"key":"S104795111300005X_ref24","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.621185"},{"key":"S104795111300005X_ref33","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.90.2.854"},{"key":"S104795111300005X_ref21","doi-asserted-by":"publisher","DOI":"10.4250\/jcu.2011.19.1.1"},{"key":"S104795111300005X_ref12","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000012626.81324.38"},{"key":"S104795111300005X_ref8","first-page":"3","article-title":"Idiopathic hypertrophic subaortic stenosis. 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