{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:58:32Z","timestamp":1758477512786},"reference-count":9,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2013,10,10]],"date-time":"2013-10-10T00:00:00Z","timestamp":1381363200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In a prospective cohort of 181 individuals followed up since childhood \u2013 when aged 9, 12 and 15 years \u2013 patients with a family history of premature coronary heart disease (n=18) had higher left ventricular mass index in adulthood \u2013 at mean age of 31 years \u2013 compared with those without (mean\u00b1standard error 39.1\u00b11.9 versus 34.6\u00b10.7 g\/m<jats:sup>2.7<\/jats:sup>, p=0.04). The correlation between adult left ventricular mass index and child triglycerides (r=0.66, p=0.04 versus r=\u22120.03, p=0.75; p<jats:sub>diff<\/jats:sub>=0.02) and diastolic blood pressure (r=0.65, p=0.02 versus r=0.16, p=0.07; p<jats:sub>diff<\/jats:sub>=0.05) was stronger among those with a family history of coronary heart disease than in those without. Although preliminary, these data suggest that the higher left ventricular mass index among adults with a family history might be explained by their increased susceptibility to child cardio-metabolic risk factors.<\/jats:p>","DOI":"10.1017\/s1047951113001571","type":"journal-article","created":{"date-parts":[[2013,10,10]],"date-time":"2013-10-10T15:40:22Z","timestamp":1381419622000},"page":"938-940","source":"Crossref","is-referenced-by-count":6,"title":["Family history of premature coronary heart disease, child cardio-metabolic risk factors and left ventricular mass"],"prefix":"10.1017","volume":"24","author":[{"given":"Costan G.","family":"Magnussen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terence","family":"Dwyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison","family":"Venn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2013,10,10]]},"reference":[{"key":"S1047951113001571_ref7","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-0584"},{"key":"S1047951113001571_ref3","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000149713.48317.27"},{"key":"S1047951113001571_ref5","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2010.246"},{"key":"S1047951113001571_ref8","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-1456"},{"key":"S1047951113001571_ref6","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.9.2159"},{"key":"S1047951113001571_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.02.044"},{"key":"S1047951113001571_ref1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000222012.56447.00"},{"key":"S1047951113001571_ref9","doi-asserted-by":"publisher","DOI":"10.3109\/07853890.2010.532152"},{"key":"S1047951113001571_ref2","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e328302f10d"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951113001571","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,21]],"date-time":"2019-04-21T20:16:34Z","timestamp":1555877794000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951113001571\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,10]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["S1047951113001571"],"URL":"https:\/\/doi.org\/10.1017\/s1047951113001571","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,10]]}}}