{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:18:14Z","timestamp":1761513494956},"reference-count":17,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2014,7,21]],"date-time":"2014-07-21T00:00:00Z","timestamp":1405900800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Antiepileptic medications have been reported to cause disturbances in cardiac conduction. Lacosamide decreases seizure burden by modulating sodium channels. Although it has been demonstrated to have few side effects, there have been reports of clinically significant cardiac conduction disturbances. We report the case of a child with hypoplastic left-heart syndrome and well-controlled multifocal atrial tachycardia who developed haemodynamically significant atrial tachycardia after receiving two doses of lacosamide.<\/jats:p>","DOI":"10.1017\/s1047951114001188","type":"journal-article","created":{"date-parts":[[2014,7,21]],"date-time":"2014-07-21T13:37:01Z","timestamp":1405949821000},"page":"806-809","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":11,"title":["Lacosamide-induced atrial tachycardia in a child with hypoplastic left-heart syndrome: the importance of assessing additional proarrhythmic risks"],"prefix":"10.1017","volume":"25","author":[{"given":"Rohit S.","family":"Loomba","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anoop K.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua","family":"Kovach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Todd M.","family":"Gudausky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,7,21]]},"reference":[{"key":"S1047951114001188_ref14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1994.tb01516.x"},{"key":"S1047951114001188_ref16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2009.02069.x"},{"key":"S1047951114001188_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(88)90282-2"},{"key":"S1047951114001188_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2012.12.009"},{"key":"S1047951114001188_ref9","doi-asserted-by":"publisher","DOI":"10.1111\/epi.12108"},{"key":"S1047951114001188_ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2007.01188.x"},{"key":"S1047951114001188_ref15","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/24.3.232"},{"key":"S1047951114001188_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2009.01.322"},{"key":"S1047951114001188_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.spen.2010.10.003"},{"key":"S1047951114001188_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2011.02.005"},{"key":"S1047951114001188_ref3","doi-asserted-by":"publisher","DOI":"10.1177\/1756285609355850"},{"key":"S1047951114001188_ref1","first-page":"187","article-title":"Efficacy and tolerability of lacosamide in the concomitant treatment of 130 patients under 16 years of age with refractory epilepsy: a prospective, open-label, observational, multicenter study in Spain","volume":"12","author":"Casas-Fernandez","year":"2012","journal-title":"Drugs RandD"},{"key":"S1047951114001188_ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2011.03212.x"},{"key":"S1047951114001188_ref11","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e318196d2b6"},{"key":"S1047951114001188_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2010.04.043"},{"key":"S1047951114001188_ref12","doi-asserted-by":"publisher","DOI":"10.1006\/geno.1996.0236"},{"key":"S1047951114001188_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2011.02.006"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951114001188","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,21]],"date-time":"2019-04-21T02:35:18Z","timestamp":1555814118000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951114001188\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,21]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["S1047951114001188"],"URL":"https:\/\/doi.org\/10.1017\/s1047951114001188","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,21]]},"assertion":[{"value":"\u00a9 Cambridge University Press 2014\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}