{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:37:19Z","timestamp":1760783839773},"reference-count":10,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2014,7,15]],"date-time":"2014-07-15T00:00:00Z","timestamp":1405382400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report a baby girl with an antenatal diagnosis of biventricular non-compaction and complete heart block detected at 22 weeks\u2019 gestation. Postnatal echocardiography confirmed severe biventricular non-compaction hypertrophic cardiomyopathy, multiple muscular ventricular septal defects, and mild\u2013moderate pulmonary valve stenosis. Skeletal muscle biopsy confirmed complex 1 mitochondrial respiratory chain deficiency. An epicardial VVI pacemaker was implanted on day 3 of life and revised at 7 years of age. She remains stable at 8 years of age following pacing and medical treatment with carvedilol, aspirin, co-enzyme Q10, and carnitine. This represents the first report of biventricular non-compaction hypertrophic phenotype in association with congenital complete heart block and complex 1 mitochondrial respiratory chain deficiency in a child.<\/jats:p>","DOI":"10.1017\/s1047951114001279","type":"journal-article","created":{"date-parts":[[2014,7,15]],"date-time":"2014-07-15T08:43:56Z","timestamp":1405413836000},"page":"1019-1021","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":4,"title":["Biventricular non-compaction hypertrophic cardiomyopathy in association with congenital complete heart block and type I mitochondrial complex deficiency"],"prefix":"10.1017","volume":"25","author":[{"given":"Ranjana","family":"Dhar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Reardon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin J.","family":"McMahon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,7,15]]},"reference":[{"key":"S1047951114001279_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-008-9359-0"},{"key":"S1047951114001279_ref7","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCGENETICS.109.903898"},{"key":"S1047951114001279_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcdr.2013.03.003"},{"key":"S1047951114001279_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(84)90618-0"},{"key":"S1047951114001279_ref2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000100664.10777.B8"},{"key":"S1047951114001279_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2013.02.004"},{"key":"S1047951114001279_ref3","first-page":"371","article-title":"Review: mitochondrial medicine \u2013 cardiomyopathy caused by defective oxidative phosphorylation","volume":"33","author":"Fosselin","year":"2003","journal-title":"Ann Clin Lab Sci"},{"key":"S1047951114001279_ref6","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.82.2.507"},{"key":"S1047951114001279_ref10","first-page":"15","article-title":"Review: metabolic cardiomopathy and conduction system defects in children","volume":"34","author":"Gilbert-Barness","year":"2004","journal-title":"Ann Clin Lab Sci"},{"key":"S1047951114001279_ref1","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1161\/01.CIR.93.5.841","article-title":"Report of the 1995 World Health Organization\/International Society and Federation of Cardiology Task Force on the definition and classification of cardiomyopathies","volume":"93","author":"Richardson","year":"1996","journal-title":"Circulation"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951114001279","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,21]],"date-time":"2019-04-21T00:35:31Z","timestamp":1555806931000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951114001279\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,15]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["S1047951114001279"],"URL":"https:\/\/doi.org\/10.1017\/s1047951114001279","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,15]]},"assertion":[{"value":"\u00a9 Cambridge University Press 2014\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}