{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T07:11:18Z","timestamp":1693984278326},"reference-count":22,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T00:00:00Z","timestamp":1418947200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aims of this study were to assess the development of heart failure in patients with congenitally corrected transposition of the great arteries in a medium-term follow-up, to identify the impact of tricuspid regurgitation on the development of heart failure, and to determine the most reliable marker for its identification. The prospective 6-year follow-up study included 19 adult patients. All patients were evaluated clinically by the determination of N-terminal pro-hormone brain natriuretic peptide levels, exercise stress testing, echocardiography magnetic resonance, or CT. Among them, two patients died of heart failure. There was a decline in exercise capacity and systolic systemic ventricular function (p=0.011). Systemic ventricular ejection fraction decreased (48.3\u00b113.7 versus 42.7\u00b112.7%, p=0.001). Tissue Doppler imaging showed a decline in peak tricuspid systolic annular velocity (10.3\u00b12.0 versus 8.3\u00b12.5 cm\/second, p=0.032) and peak tricuspid early diastolic annular velocity (14.6\u00b14.3 versus 12.0\u00b14.5 cm\/second, p=0.048). The tricuspid regurgitation did not increase significantly. N-terminal pro-hormone brain natriuretic peptide levels increased (127.0 ng\/L(82.3\u2013305.8) versus 226.0 ng\/L(112.5\u2013753.0), p=0.022). Progressive exercise intolerance in congenitally corrected transposition of the great arteries appears to be driven mainly by a progression in systemic right ventricular dysfunction. Tricuspid regurgitation is likely to play a role, especially in patients with structural abnormalities of the tricuspid valve \u2013 Ebstein anomaly. The N-terminal pro-hormone brain natriuretic peptide levels and tissue Doppler parameters appear sensitive in detecting changes over time and may guide management.<\/jats:p>","DOI":"10.1017\/s1047951114002479","type":"journal-article","created":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T11:24:06Z","timestamp":1418988246000},"page":"1332-1339","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":2,"title":["A 6-year follow-up study of adult patients with congenitally corrected transposition"],"prefix":"10.1017","volume":"25","author":[{"given":"Mirta","family":"Ko\u017eelj","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Cviji\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pavel","family":"Berden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toma\u017e","family":"Podnar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,12,19]]},"reference":[{"key":"S1047951114002479_ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2009.08.038"},{"key":"S1047951114002479_ref10","doi-asserted-by":"publisher","DOI":"10.1159\/000073839"},{"key":"S1047951114002479_ref19","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.10.997"},{"key":"S1047951114002479_ref9","first-page":"933","article-title":"Doppler tissue imaging of the right ventricle","volume":"95","author":"Suty-Selton","year":"2002","journal-title":"Arch Mal Coeur Vaiss"},{"key":"S1047951114002479_ref4","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951108003119"},{"key":"S1047951114002479_ref18","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.529800"},{"key":"S1047951114002479_ref5","doi-asserted-by":"crossref","first-page":"2915","DOI":"10.1093\/eurheartj\/ehq249","article-title":"ESC guidelines for the management of grown-up congenital heart disease (new version 2010)","volume":"31","author":"Baumgartner","year":"2010","journal-title":"Eur Heart J"},{"key":"S1047951114002479_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2014.04.129"},{"key":"S1047951114002479_ref12","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.10262"},{"key":"S1047951114002479_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2013.02.030"},{"key":"S1047951114002479_ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-011-2345-6"},{"key":"S1047951114002479_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2012.04.005"},{"key":"S1047951114002479_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2012.08.014"},{"key":"S1047951114002479_ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1542-474X.2004.93003.x"},{"key":"S1047951114002479_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(89)90268-8"},{"key":"S1047951114002479_ref8","doi-asserted-by":"publisher","DOI":"10.1053\/je.1999.v12.a99246"},{"key":"S1047951114002479_ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-001-0037-8"},{"key":"S1047951114002479_ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2010.01.007"},{"key":"S1047951114002479_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00682-3"},{"key":"S1047951114002479_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.11.021"},{"key":"S1047951114002479_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2005.10.005"},{"key":"S1047951114002479_ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s002469910006"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951114002479","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,20]],"date-time":"2019-04-20T19:28:46Z","timestamp":1555788526000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951114002479\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,19]]},"references-count":22,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["S1047951114002479"],"URL":"https:\/\/doi.org\/10.1017\/s1047951114002479","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,19]]},"assertion":[{"value":"\u00a9 Cambridge University Press 2014\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}