{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,2,5]],"date-time":"2023-02-05T05:28:03Z","timestamp":1675574883320},"reference-count":18,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2015,3,3]],"date-time":"2015-03-03T00:00:00Z","timestamp":1425340800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951115000219_abs1\" sec-type=\"general\"><jats:title>Objective<\/jats:title><jats:p>Multiplanar re-formatting of full-volume three-dimensional echocardiography data sets offers new insights into the morphology of atrioventricular septal defects. We hypothesised that distortion of the alignment between the atrial and ventricular septums results in imbalanced venous return to the ventricles, with consequent proportional ventricular hypoplasia.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951115000219_abs2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>A single observer evaluated 31 patients, with a mean age of 52.09 months, standard deviation of 55, and with a range from 2 to 264 months, with atrioventricular septal defects, of whom 17 were boys. Ventricular imbalance, observed in nine patients, was determined by two-dimensional assessment, and confirmed at surgical inspection in selected cases when a univentricular strategy was undertaken. Offline analysis using multiplanar re-formatting was performed. A line was drawn though the length of the ventricular septum and a second line along the plane of the atrial septum, taking the angle between these two lines as the atrioventricular septal angle. We compared the angle between 22 patients with adequately sized ventricles, and those with ventricular imbalance undergoing univentricular repair.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951115000219_abs3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>In the 22 patients undergoing biventricular repair, the septal angle was 0 in 14 patients; the other eight patients having angles ranging from 1 to 36, with a mean angle of 7.4\u00b0, and standard deviation of 11.1\u00b0.The mean angle in the nine patients with ventricle imbalance was 28.6\u00b0, with a standard deviation of 3.04\u00b0, and with a range from 26 to 35\u00b0. Of those undergoing univentricular repair, two patients died, with angles of 26 and 30\u00b0, respectively.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951115000219_abs4\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>The atrioventricular septal angle derived via multiplanar formatting gives important information regarding the degree of ventricular hypoplasia and imbalance. When this angle is above 25\u00b0, patients are likely to have ventricular imbalance requiring univentricular repair.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951115000219","type":"journal-article","created":{"date-parts":[[2015,3,3]],"date-time":"2015-03-03T07:27:24Z","timestamp":1425367644000},"page":"321-326","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":5,"title":["The angulation of the septal structures impacts ventricular imbalance in atrioventricular septal defects with a common atrioventricular junction"],"prefix":"10.1017","volume":"26","author":[{"given":"Zaheer","family":"Ahmad","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zek","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Roman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus","family":"Haw","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert H.","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Vettukattil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2015,3,3]]},"reference":[{"key":"S1047951115000219_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(96)00262-8"},{"key":"S1047951115000219_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2008.04.106"},{"key":"S1047951115000219_ref5","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8175.2001.00415.x"},{"key":"S1047951115000219_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2006.09.080"},{"key":"S1047951115000219_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2008.05.006"},{"key":"S1047951115000219_ref18","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.112.000189"},{"key":"S1047951115000219_ref3","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951100004613"},{"key":"S1047951115000219_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(73)90148-8"},{"key":"S1047951115000219_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S1058-9813(99)00030-2"},{"key":"S1047951115000219_ref17","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.925636"},{"key":"S1047951115000219_ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2006.00193.x"},{"key":"S1047951115000219_ref10","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8175.2003.00018.x"},{"key":"S1047951115000219_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.07.047"},{"key":"S1047951115000219_ref2","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0022-5223(19)35266-3","article-title":"Atrioventricular septal defects with severe left ventricular hypoplasia","volume":"96","author":"Corno","year":"1988","journal-title":"J Thorac Cardiovasc Surg"},{"key":"S1047951115000219_ref4","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951106000758"},{"key":"S1047951115000219_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2004.07.010"},{"key":"S1047951115000219_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00351-3"},{"key":"S1047951115000219_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2009.09.027"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951115000219","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T12:38:51Z","timestamp":1598791131000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951115000219\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,3]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["S1047951115000219"],"URL":"https:\/\/doi.org\/10.1017\/s1047951115000219","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,3]]},"assertion":[{"value":"\u00a9 Cambridge University Press 2015\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}