{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T11:47:43Z","timestamp":1769168863718,"version":"3.49.0"},"reference-count":20,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2015,10,16]],"date-time":"2015-10-16T00:00:00Z","timestamp":1444953600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951115002188_abs1\" sec-type=\"intro\"><jats:title>Introduction<\/jats:title><jats:p>Non-invasive peripheral pulse oximeters are routinely used to measure oxyhaemoglobin saturation (SpO<jats:sub>2<\/jats:sub>) in cyanotic congenital heart disease. These probes are calibrated in healthy adult volunteers between arterial saturations of ~75 and 100%, using the gold standard of co-oximetry on arterial blood samples. There are little data to attest their accuracy in cyanotic congenital heart disease.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951115002188_abs2\" sec-type=\"general\"><jats:title>Aims<\/jats:title><jats:p>We aimed to assess the accuracy of a commonly used probe in children with cyanotic congenital heart disease.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951115002188_abs3\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>Children with cyanotic congenital heart disease admitted to the Paediatric Intensive Care Unit with an arterial line in situ were included to our study. Prospective simultaneous recordings of SpO<jats:sub>2<\/jats:sub>, measured by the Masimo SET<jats:sup>\u00ae<\/jats:sup> LNCS Neo peripheral probe, and co-oximeter saturations (SaO<jats:sub>2<\/jats:sub>) measured by arterial blood gas analysis were recorded.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951115002188_abs4\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>A total of 527 paired measurements of SpO<jats:sub>2<\/jats:sub> and SaO<jats:sub>2<\/jats:sub> (using an ABL800 FLEX analyser) in 25 children were obtained. The mean bias of the pulse oximeter for all SaO<jats:sub>2<\/jats:sub> readings was +4.7\u00b113.8%. The wide standard deviation indicates poor precision. This mean bias increased to +7.0\u00b113.7% at SaO<jats:sub>2<\/jats:sub> recordings &lt;75%. The accuracy root mean square of the recordings was 3.30% across all saturation levels, and this increased to 4.98% at SaO<jats:sub>2<\/jats:sub> &lt;75%.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951115002188_abs5\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>The performance of the Masimo SET<jats:sup>\u00ae<\/jats:sup> LNCS Neo pulse oximeter is poor when arterial oxyhaemoglobin saturations are below 75%. It tends to overestimate saturations in children with cyanotic congenital heart disease. This may have serious implications for clinical decisions.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951115002188","type":"journal-article","created":{"date-parts":[[2015,10,16]],"date-time":"2015-10-16T01:56:03Z","timestamp":1444960563000},"page":"1183-1186","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":17,"title":["Accuracy of the Masimo SET<sup>\u00ae<\/sup> LNCS neo peripheral pulse oximeter in cyanotic congenital heart disease"],"prefix":"10.1017","volume":"26","author":[{"given":"Michael J.","family":"Griksaitis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gemma E.","family":"Scrimgeour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John V.","family":"Pappachan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew J.","family":"Baldock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2015,10,16]]},"reference":[{"key":"#cr-split#-S1047951115002188_ref2.1","unstructured":"1. The Association of Anaesthetists of Great Britain and Ireland. Recommendations for standards of monitoring during anaesthesia and recovery, 2007"},{"key":"#cr-split#-S1047951115002188_ref2.2","unstructured":"2. 4th edn. Retrieved April 23, 2015, from http:\/\/www.aagbi.org\/sites\/default\/files\/standardsofmonitoring07.pdf"},{"key":"S1047951115002188_ref3","first-page":"261","article-title":"Pulse oximetry","volume":"46","author":"Kamat","year":"2002","journal-title":"Indian J Anaesth"},{"key":"S1047951115002188_ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2011.07021.x"},{"key":"S1047951115002188_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0147-9563(98)90086-3"},{"key":"S1047951115002188_ref8","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2013-305091"},{"key":"S1047951115002188_ref19","doi-asserted-by":"crossref","first-page":"531","DOI":"10.4103\/0019-5049.72642","article-title":"Pulse oximeter accuracy and precision at five different sensor locations in infants and children with cyanotic heart disease","volume":"54","author":"Das","year":"2010","journal-title":"Indian J Anaesth"},{"key":"S1047951115002188_ref17","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198711000-00015"},{"key":"S1047951115002188_ref16","doi-asserted-by":"publisher","DOI":"10.1177\/0885066604263819"},{"key":"S1047951115002188_ref12","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-1760"},{"key":"S1047951115002188_ref14","doi-asserted-by":"publisher","DOI":"10.1080\/10543400701329422"},{"key":"S1047951115002188_ref9","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2013.842550"},{"key":"S1047951115002188_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/1053-0770(93)90120-A"},{"key":"S1047951115002188_ref18","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e3181727967"},{"key":"S1047951115002188_ref13","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-1749"},{"key":"S1047951115002188_ref10","doi-asserted-by":"publisher","DOI":"10.1111\/anae.12382"},{"key":"S1047951115002188_ref4","unstructured":"U.S. Food and Drug Administration. 510(k) clearances, 2009. Retrieved July 10, 2014, from http:\/\/www.accessdata.fda.gov\/scripts\/cdrh\/devicesatfda\/index.cfm?Search_Term=Oximeter%2E"},{"key":"S1047951115002188_ref7","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2012-302045"},{"key":"S1047951115002188_ref1","unstructured":"American Society of Anesthesiologists. Committee of Standards and Practice Parameters. Standards for basic anesthetic monitoring, 2011. Retrieved April 23, 2015, from https:\/\/www.asahq.org\/resources\/standards-and-guidelines."},{"key":"S1047951115002188_ref15","doi-asserted-by":"publisher","DOI":"10.1002\/sim.3086"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951115002188","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,18]],"date-time":"2019-04-18T21:40:21Z","timestamp":1555623621000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951115002188\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,16]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["S1047951115002188"],"URL":"https:\/\/doi.org\/10.1017\/s1047951115002188","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10,16]]},"assertion":[{"value":"\u00a9 Cambridge University Press 2015\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}