{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T07:14:28Z","timestamp":1781075668235,"version":"3.54.1"},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2015,11,16]],"date-time":"2015-11-16T00:00:00Z","timestamp":1447632000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951115002243_abs1\" sec-type=\"general\"><jats:title>Background<\/jats:title><jats:p>Different echocardiographic parameters have been studied and validated for assessing the severity of mitral stenosis; however, scant data are available for these markers in the context of balloon mitral valvuloplasty in juvenile age groups (ages \u2a7d20 years).<\/jats:p><\/jats:sec><jats:sec id=\"S1047951115002243_abs2\" sec-type=\"objectives\"><jats:title>Objectives<\/jats:title><jats:p>The aim of the present study was to find out the utility of echocardiographic parameters such as mitral valve separation index, left atrial volume, right ventricular systolic pressure, tricuspid annular plane systolic excursion, tricuspid annular systolic velocity, and right ventricular Tei index in predicting success of balloon mitral valvuloplasty and their relation to mitral valve area in juvenile mitral stenosis.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951115002243_abs3\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>We carried out a prospective single-centre study involving 52 juvenile mitral stenosis patients undergoing elective valvuloplasty. Success was defined as an increase in mitral valve area \u2a7e50% or \u2a7e1.5 cm<jats:sup>2<\/jats:sup>. Echocardiographic measurements were taken before and 24 hours after the procedure and statistical analyses were carried out.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951115002243_abs4\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>The mean age of the study population was 14.3 years (SD \u00b14.55), ranging from 7 to 20 years. Valvuloplasty was successful in 49 out of 52 patients. The mean valve area improved from 0.89 (SD \u00b10.16) to 1.73 (SD \u00b10.22) cm<jats:sup>2<\/jats:sup>\/m<jats:sup>2<\/jats:sup>(p&lt;0.01), and the mean mitral valve gradient decreased from 19.87 (SD \u00b17.89) to 7.45 (SD \u00b12.07) (p=0.021). All the surrogate parameters improved favourably after valvuloplasty (p&lt;0.01). The decrease in right ventricular systolic pressure was a better indicator of the success followed by the increase in valve separation index (area under the curve 0.81 and 0.76, respectively).<\/jats:p><\/jats:sec><jats:sec id=\"S1047951115002243_abs5\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>All the surrogate markers studied showed favourable improvement, and right ventricular systolic pressure reduction and improved mitral valve separation index were better indicators of successful valvuloplasty.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951115002243","type":"journal-article","created":{"date-parts":[[2015,11,16]],"date-time":"2015-11-16T09:13:31Z","timestamp":1447665211000},"page":"1266-1273","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Echocardiographic parameters for assessing successful balloon mitral valvuloplasty in juvenile age groups"],"prefix":"10.1017","volume":"26","author":[{"given":"Ajith","family":"Ananthakrishna Pillai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geofi","family":"George","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harichandrakumar","family":"Kottyen Thazhath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sreekanth","family":"Yerram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2015,11,16]]},"reference":[{"key":"S1047951115002243_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(91)90060-X"},{"key":"S1047951115002243_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/BF01137717"},{"key":"S1047951115002243_ref9","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.209.285"},{"key":"S1047951115002243_ref10","first-page":"627","article-title":"Echocardiographic right ventricular function assessment before and after successful percutaneous mitral commissurotomy","volume":"20","author":"Bensaid","year":"2011","journal-title":"J Heart Valve Dis"},{"key":"S1047951115002243_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2005.02.012"},{"key":"S1047951115002243_ref4","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jeq194"},{"key":"S1047951115002243_ref1","first-page":"563","article-title":"Mitral leaflet separation index \u2013 a simple novel index to assess the severity of mitral stenosis","volume":"60","author":"Vimal Raj","year":"2008","journal-title":"Indian Heart J"},{"key":"S1047951115002243_ref19","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.79.5.1061"},{"key":"S1047951115002243_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2010.05.010"},{"key":"S1047951115002243_ref2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.95.6.1686"},{"key":"S1047951115002243_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2008.03.050"},{"key":"S1047951115002243_ref18","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.75.4.778"},{"key":"S1047951115002243_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2005.10.012"},{"key":"S1047951115002243_ref15","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0022-5223(19)35295-X","article-title":"Pulmonary vascular dynamics after percutaneous mitral valvotomy","volume":"96","author":"Block","year":"1988","journal-title":"J Thorac Cardiovasc Surg"},{"key":"S1047951115002243_ref11","doi-asserted-by":"publisher","DOI":"10.1111\/echo.12256"},{"key":"S1047951115002243_ref5","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1979.03630410012009"},{"key":"S1047951115002243_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2005.07.012"},{"key":"S1047951115002243_ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2012.01787.x"},{"key":"S1047951115002243_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-7317(97)70086-5"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951115002243","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,11]],"date-time":"2020-09-11T11:49:13Z","timestamp":1599824953000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951115002243\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,16]]},"references-count":19,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["S1047951115002243"],"URL":"https:\/\/doi.org\/10.1017\/s1047951115002243","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11,16]]},"assertion":[{"value":"\u00a9 Cambridge University Press 2015\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}