{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:25:23Z","timestamp":1787239523234,"version":"build-2736575974"},"reference-count":18,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T00:00:00Z","timestamp":1491350400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S1047951117000087_abs1\" sec-type=\"general\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The relationship between interatrial communication, ductus arteriosus, and pulmonary flow in transposition of the great arteries and intact ventricular septum may help predict postnatal desaturation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951117000087_abs2\" sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Echocardiographic data of 45 fetuses with transposition of the great arteries and intact ventricular septum and 50 age-matched controls were retrospectively reviewed. Interatrial communication, left and right ventricular output, flow in the ductus arteriosus, as well as effective pulmonary flow were measured. Patients were divided into two groups on the basis of postnatal saturations: group 1 had saturations \u2a7d50% and group 2 &gt;50%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951117000087_abs3\" sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 45 fetuses, 13 (26.7%) were classified into group 1. Compared with fetuses in group 2, they had a smaller interatrial communication (2.9 versus 4.0 mm, p=0.004) and more retrograde diastolic flow in the ductus arteriosus (92 versus 23%, p=0.002). Both groups showed a significant decrease in ductal flow compared with controls. Patients in group 2 had a higher effective pulmonary flow compared with controls. There was a mild correlation between left ventricular output and size of the interatrial communication (Spearman\u2019s rank correlation 0.44).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S1047951117000087_abs4\" sec-type=\"conclusion\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A retrograde diastolic flow is present in most of the fetuses with postnatal desaturation. Fetuses with transposition of the great arteries have a lower flow through the ductus arteriosus compared with controls. Fetuses without restrictive foramen ovale have higher effective pulmonary flow. Peripheral pulmonary vasodilatation due to higher oxygen saturation in pulmonary arteries in the case of transposition of the great arteries could be one possible cause.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s1047951117000087","type":"journal-article","created":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T05:04:52Z","timestamp":1491368692000},"page":"1280-1288","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":11,"title":["Relationship between interatrial communication, ductus arteriosus, and pulmonary flow patterns in fetuses with transposition of the great arteries: prediction of neonatal desaturation"],"prefix":"10.1017","volume":"27","author":[{"given":"Laurence","family":"Vaujois","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Boucoiran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Preuss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myriam","family":"Brassard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Houde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean C.","family":"Fouron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Jos\u00e9e","family":"Raboisson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2017,4,5]]},"reference":[{"key":"S1047951117000087_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(91)90611-C"},{"key":"S1047951117000087_ref5","doi-asserted-by":"publisher","DOI":"10.1161\/hc1102.105232"},{"key":"S1047951117000087_ref18","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.97.3.257"},{"key":"S1047951117000087_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90288-X"},{"key":"S1047951117000087_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2008.09.001"},{"key":"S1047951117000087_ref1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.7.916"},{"key":"S1047951117000087_ref6","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000144141.18560.CF"},{"key":"S1047951117000087_ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-012-0575-2"},{"key":"S1047951117000087_ref14","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-3-27"},{"key":"S1047951117000087_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-7317(14)80366-0"},{"key":"S1047951117000087_ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-009-9475-5"},{"key":"S1047951117000087_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(79)90412-0"},{"key":"S1047951117000087_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2010.12.020"},{"key":"S1047951117000087_ref15","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-3783"},{"key":"S1047951117000087_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00310-6"},{"key":"S1047951117000087_ref17","first-page":"375","article-title":"Aorto pulmonary transposition in the fetus: speculation on pathophysiology and therapy","volume":"61","author":"Rudolph","year":"2009","journal-title":"Pediatr Cardiol"},{"key":"S1047951117000087_ref9","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.75.2.406"},{"key":"S1047951117000087_ref4","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.9.1209"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951117000087","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,16]],"date-time":"2019-04-16T21:43:28Z","timestamp":1555451008000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951117000087\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,5]]},"references-count":18,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["S1047951117000087"],"URL":"https:\/\/doi.org\/10.1017\/s1047951117000087","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,5]]},"assertion":[{"value":"\u00a9 Cambridge University Press 2017\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}