{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:47:07Z","timestamp":1792100827121,"version":"4.4.0"},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2017,6,27]],"date-time":"2017-06-27T00:00:00Z","timestamp":1498521600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951117000804_abs1\" sec-type=\"general\"><jats:title>Background<\/jats:title><jats:p>Pulmonary balloon valvuloplasty is a safe and effective treatment for children with pulmonary valve stenosis. A few studies evaluate the long-term outcomes of the procedure, particularly the degree of pulmonary regurgitation. We evaluated the outcomes of children &gt;1 year following valvuloplasty for pulmonary valve stenosis.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951117000804_abs2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis of children with pulmonary valve stenosis following pulmonary balloon valvuloplasty at a single institution was performed. Clinic summaries, catheterisation data, and echocardiographic data were reviewed. Inclusion criteria were isolated pulmonary valve stenosis, age &lt;19 years at the time of intervention, and at least one echocardiogram performed at least 1 year after valvuloplasty.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951117000804_abs3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>A total of 53 patients met inclusion criteria. The median age at valvuloplasty was 0.4 years (0.01\u201310.6 years). The last follow-up was 4.8\u00b12.3 years following valvuloplasty. The pre-valvuloplasty peak instantaneous gradient by echocardiography was 60.6\u00b114.6 mmHg. The peak gradient at the first postoperative echocardiography was reduced to 25.5\u00b112 mmHg (p&lt;0.001), and further decreased to 14.8\u00b115.8 mmHg (p&lt;0.001) at the most recent follow-up. The degree of regurgitation increased from before valvuloplasty to after valvuloplasty (p&lt;0.001) but did not progress at the most recent follow-up (p=0.17). Only three patients (5.7%) required re-intervention for increasing pulmonary stenosis (two surgical; one repeat balloon). No significant procedural complications occurred.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951117000804_abs4\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>Pulmonary balloon valvuloplasty remains a safe and effective treatment for children with isolated pulmonary valve stenosis, with excellent long-term outcomes and no mortality. A few patients require further intervention. Long-term follow-up demonstrates decreased, residual stenosis. Patients have a small, acute increase in pulmonary regurgitation following valvuloplasty, but no long-term progression.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951117000804","type":"journal-article","created":{"date-parts":[[2017,6,27]],"date-time":"2017-06-27T08:49:43Z","timestamp":1498553383000},"page":"1566-1570","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":7,"title":["Results of pulmonary balloon valvuloplasty persist and improve at late follow-up in isolated pulmonary valve stenosis"],"prefix":"10.1017","volume":"27","author":[{"given":"John J.","family":"Parent","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael M.","family":"Ross","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edgard A.","family":"Bendaly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Breinholt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2017,6,27]]},"reference":[{"key":"S1047951117000804_ref11","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1017\/S1047951103000933","article-title":"Pulmonary regurgitation after percutaneous balloon valvuloplasty for isolated pulmonary valvar stenosis in childhood","volume":"13","author":"Poon","year":"2003","journal-title":"Cardiol Young"},{"key":"S1047951117000804_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(86)80434-X"},{"key":"S1047951117000804_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s002469900240"},{"key":"S1047951117000804_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(03)00678-7"},{"key":"S1047951117000804_ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8183.2001.tb00343.x"},{"key":"S1047951117000804_ref12","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.80.6.591"},{"key":"S1047951117000804_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(99)70022-0"},{"key":"S1047951117000804_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(93)90727-I"},{"key":"S1047951117000804_ref5","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20982"},{"key":"S1047951117000804_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90154-F"},{"key":"S1047951117000804_ref10","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.89.4.1751"},{"key":"S1047951117000804_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01886-7"},{"key":"S1047951117000804_ref13","first-page":"318","article-title":"Late outcomes after pulmonary valve balloon dilatation in neonates, infants and children","volume":"17","author":"Garty","year":"2005","journal-title":"J Invasive Cardiol"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951117000804","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,27]],"date-time":"2019-09-27T05:32:49Z","timestamp":1569562369000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951117000804\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,27]]},"references-count":13,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["S1047951117000804"],"URL":"https:\/\/doi.org\/10.1017\/s1047951117000804","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,27]]},"assertion":[{"value":"\u00a9 Cambridge University Press 2017\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}