{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T12:44:12Z","timestamp":1740141852744,"version":"3.37.3"},"reference-count":11,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2017,8,29]],"date-time":"2017-08-29T00:00:00Z","timestamp":1503964800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Premature ventricular contractions are a rare side effect of filgrastim, reported mainly in elderly men. Here we report the case of a 9-year-old child with thalassaemia who developed frequent premature ventricular contractions after three doses of filgrastim were given for deferiprone-induced agranulocytosis. The arrhythmia resolved 3 weeks after discontinuation of filgrastim. Children treated with filgrastim should be carefully monitored for potentially serious arrhythmia.<\/jats:p>","DOI":"10.1017\/s1047951117001585","type":"journal-article","created":{"date-parts":[[2017,8,29]],"date-time":"2017-08-29T02:13:00Z","timestamp":1503972780000},"page":"155-158","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Premature ventricular contractions as a side effect of filgrastim in a child with B-thalassaemia"],"prefix":"10.1017","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8324-7364","authenticated-orcid":false,"given":"Hanan F.","family":"Nazir","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niranjan","family":"Joshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasser A.","family":"Wali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2017,8,29]]},"reference":[{"key":"S1047951117001585_ref9","doi-asserted-by":"publisher","DOI":"10.4103\/0976-500X.92508"},{"key":"S1047951117001585_ref1","doi-asserted-by":"publisher","DOI":"10.3109\/03630269.2010.484791"},{"key":"S1047951117001585_ref8","doi-asserted-by":"publisher","DOI":"10.1159\/000331711"},{"key":"S1047951117001585_ref10","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00077.2009"},{"key":"S1047951117001585_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardiores.2004.10.008"},{"key":"S1047951117001585_ref5","unstructured":"Keany JE. Premature ventricular contraction. Retrieved January 13, 2017, from Emedicine.medscape.com\/article\/761148-overview."},{"key":"S1047951117001585_ref6","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eun121"},{"key":"S1047951117001585_ref11","doi-asserted-by":"publisher","DOI":"10.2165\/00044011-200929080-00005"},{"key":"S1047951117001585_ref4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198501243120401"},{"key":"S1047951117001585_ref2","first-page":"275","article-title":"Agranulocytosis in beta thalassemia major patients treated with oral iron chelating agent deferiprone","volume":"23","author":"Wali","year":"2008","journal-title":"Oman Med J"},{"key":"S1047951117001585_ref3","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.24479"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951117001585","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T17:27:38Z","timestamp":1555349258000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951117001585\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,29]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["S1047951117001585"],"URL":"https:\/\/doi.org\/10.1017\/s1047951117001585","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"type":"print","value":"1047-9511"},{"type":"electronic","value":"1467-1107"}],"subject":[],"published":{"date-parts":[[2017,8,29]]},"assertion":[{"value":"\u00a9 Cambridge University Press 2017\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}