{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T08:13:28Z","timestamp":1769156008415,"version":"3.49.0"},"reference-count":7,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2018,1,10]],"date-time":"2018-01-10T00:00:00Z","timestamp":1515542400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951117002827_abs1\" sec-type=\"general\"><jats:title\/><jats:p>Pulmonary valve stenosis is common in patients with Noonan\u2019s syndrome. The response to balloon valvoplasty varies.<\/jats:p><jats:p>We assessed the correlation between re-intervention rate, immediate response, and the progress of the valve gradient over time after intervention.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951117002827_abs2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>This is a retrospective study conducted from 1995 to 2014.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951117002827_abs3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Of 14 patients identified, seven had re-intervention 28\u00b154 months (range 3\u2013149, median 3.3) after valvoplasty. These patients did not have a significant decrease in gradient after intervention. Their gradient subsequently decreased during follow-up and then became static before increasing years after intervention. In contrast, the gradient of patients not requiring further intervention continually reduced over time. Demographics did not differ between these groups.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951117002827_abs4\" sec-type=\"conclusion\"><jats:title>Conclusion<\/jats:title><jats:p>We could not identify predisposing factors for long-term success of pulmonary valvoplasty in Noonan\u2019s patients, but the trajectory of gradients differs significantly between patients needing re-intervention from those who remain free from re-intervention.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951117002827","type":"journal-article","created":{"date-parts":[[2018,1,10]],"date-time":"2018-01-10T07:11:55Z","timestamp":1515568315000},"page":"647-652","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":17,"title":["Results of balloon pulmonary valvoplasty in children with Noonan\u2019s syndrome"],"prefix":"10.1017","volume":"28","author":[{"given":"Jonathon","family":"Holzmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shane M.","family":"Tibby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Rosenthal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shakeel","family":"Qureshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gareth","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Krasemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2018,1,10]]},"reference":[{"key":"S1047951117002827_ref3","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.83.6.1915"},{"key":"S1047951117002827_ref4","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.80.6.591"},{"key":"S1047951117002827_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(93)90727-I"},{"key":"S1047951117002827_ref5","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.89.4.1751"},{"key":"S1047951117002827_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(99)70022-0"},{"key":"S1047951117002827_ref1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2013-305047"},{"key":"S1047951117002827_ref6","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2006.104547"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951117002827","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,14]],"date-time":"2019-04-14T21:39:05Z","timestamp":1555277945000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951117002827\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,10]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,5]]}},"alternative-id":["S1047951117002827"],"URL":"https:\/\/doi.org\/10.1017\/s1047951117002827","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,10]]},"assertion":[{"value":"\u00a9 Cambridge University Press 2018\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}