{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T20:56:02Z","timestamp":1778619362391,"version":"3.51.4"},"reference-count":44,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T00:00:00Z","timestamp":1559606400000},"content-version":"unspecified","delay-in-days":34,"URL":"https:\/\/www.cambridge.org\/core\/terms"},{"start":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T00:00:00Z","timestamp":1559606400000},"content-version":"unspecified","delay-in-days":34,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951119000350_as1\"><jats:title>Introduction:<\/jats:title><jats:p>Atrial septal defect is the third most common CHD. A hemodynamically significant atrial septal defect causes volume overload of the right side of the heart. Preterm children may suffer from both pulmonary and cardiac comorbidities, including altered myocardial function. The aim of this study was to compare the rate of adverse events following atrial septal defect closure in preterm- and term-born children.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951119000350_as2\"><jats:title>Method:<\/jats:title><jats:p>We performed a retrospective cohort study including children born in Sweden, who had a surgical or percutaneous atrial septal defect closure at the children\u2019s hospitals in Lund and Stockholm, between 2000 and 2014, assessing time to the first event within 1 month or 1 year. We analysed differences in the number of and the time to events between the preterm and term cohort using the Kaplan\u2013Meier survival curve, a generalised model applying zero-inflated Poisson distribution and Gary-Anderson\u2019s method.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951119000350_as3\"><jats:title>Results:<\/jats:title><jats:p>Overall, 413 children were included in the study. Of these, 93 (22.5%) were born prematurely. The total number of adverse events was 178 (110 minor and 68 major). There was no difference between the cohorts in the number of events, whether within 1 month or within a year, between major (p = 0.69) and minor (p = 0.84) events or frequencies of multiple events (p = 0.92).<\/jats:p><\/jats:sec><jats:sec id=\"S1047951119000350_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>Despite earlier procedural age, larger atrial septal defects, and higher comorbidity than term children, preterm children appear to have comparable risk for complications during the first year after surgical or percutaneous closure.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951119000350","type":"journal-article","created":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T04:47:44Z","timestamp":1559623664000},"page":"626-636","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":8,"title":["Adverse events within 1 year after surgical and percutaneous closure of atrial septal defects in preterm children"],"prefix":"10.1017","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8785-3318","authenticated-orcid":false,"given":"Gustaf","family":"Tangh\u00f6j","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petru","family":"Liuba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunnar","family":"Sj\u00f6berg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annika","family":"Rydberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Estelle","family":"Naumburg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2019,6,4]]},"reference":[{"key":"S1047951119000350_ref40","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2013-305185"},{"key":"S1047951119000350_ref43","doi-asserted-by":"publisher","DOI":"10.1177\/140349489001800209"},{"key":"S1047951119000350_ref44","doi-asserted-by":"publisher","DOI":"10.1186\/s40949-017-0013-7"},{"key":"S1047951119000350_ref22","first-page":"95","volume-title":"Graviditeter, 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Thil\u00e9n U , Jeremiasen I , Bj\u00f6rkhem G , et al. Nationellt register f\u00f6r medf\u00f6dda hj\u00e4rtsjukdomar, 2016. 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