{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T21:58:45Z","timestamp":1747173525325,"version":"3.40.5"},"reference-count":16,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T00:00:00Z","timestamp":1560816000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"},{"start":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T00:00:00Z","timestamp":1560816000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Elevated left ventricular end diastolic pressure is a risk factor for ventricular arrhythmias in patients with tetralogy of Fallot. The objective of this retrospective study was to identify echocardiographic measures associated with left ventricular end diastolic pressure &gt;12 mmHg in this population. Repaired tetralogy of Fallot patients age \u226513 years, who underwent a left heart catheterisation within 7 days of having an echocardiogram were evaluated. Univariate comparison was made in echocardiographic and clinical variables between patients with left ventricular end diastolic pressure &gt;12 versus \u226412 mmHg. Ninety-four patients (54% male) with a median age of 24.6 years were included. Thirty-four (36%) had left ventricular end diastolic pressure &gt;12 mmHg. Patients with left ventricular end diastolic pressure &gt;12mmHg were older (median 32.9 versus 24.0 years, p = 0.02), more likely to have a history of an aortopulmonary shunt (62% versus 38%, p = 0.03), and have a diagnosis of hypertension (24% versus 7%, p = 0.03) compared to those with left ventricular end diastolic pressure \u226412 mmHg. There were no significant differences in mitral valve E\/A ratio, annular e\u2019 velocity, or E\/e\u2019 ratio between patients with left ventricular end diastolic pressure &gt;12 versus \u226412 mmHg. Patients with left ventricular end diastolic pressure &gt;12mmHg had larger left atrial area (mean 17.7 versus 14.0 cm<jats:sup>2<\/jats:sup>, p = 0.03) and larger left atrium anterior\u2013posterior diameter (mean 36.0 versus 30.6 mm, p = 0.004). In conclusion, typical echocardiographic measures of left ventricular diastolic dysfunction may not be reliable in tetralogy of Fallot patients. Prospective studies with the use of novel echocardiographic measures are needed.<\/jats:p>","DOI":"10.1017\/s1047951119001331","type":"journal-article","created":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T04:00:46Z","timestamp":1560830446000},"page":"1020-1024","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":2,"title":["Echocardiographic predictors of elevated left ventricular end diastolic pressure in adolescent and adult patients with repaired tetralogy of Fallot"],"prefix":"10.1017","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6401-9980","authenticated-orcid":false,"given":"Adam M.","family":"Lubert","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy B.","family":"Cotts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey D.","family":"Zampi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunkyung","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark D.","family":"Norris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2019,6,18]]},"reference":[{"key":"S1047951119001331_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02714-8"},{"key":"S1047951119001331_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2010.08.021"},{"key":"S1047951119001331_ref12","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2015.00003"},{"key":"S1047951119001331_ref13","doi-asserted-by":"publisher","DOI":"10.1111\/echo.12437"},{"key":"S1047951119001331_ref8","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jew082"},{"key":"S1047951119001331_ref3","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.726372"},{"key":"S1047951119001331_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)00381-9"},{"key":"S1047951119001331_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2017.02.153"},{"key":"S1047951119001331_ref15","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jes067"},{"key":"S1047951119001331_ref7","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.928481"},{"key":"S1047951119001331_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2012.05.011"},{"key":"S1047951119001331_ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s002460010178"},{"key":"S1047951119001331_ref2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1013719"},{"key":"S1047951119001331_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2016.01.011"},{"key":"S1047951119001331_ref5","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2003.029280"},{"key":"S1047951119001331_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2012.11.003"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951119001331","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,27]],"date-time":"2019-08-27T09:20:51Z","timestamp":1566897651000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951119001331\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,18]]},"references-count":16,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["S1047951119001331"],"URL":"https:\/\/doi.org\/10.1017\/s1047951119001331","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"type":"print","value":"1047-9511"},{"type":"electronic","value":"1467-1107"}],"subject":[],"published":{"date-parts":[[2019,6,18]]},"assertion":[{"value":"\u00a9 Cambridge University Press 2019\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}