{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T15:17:49Z","timestamp":1784819869829,"version":"3.55.0"},"reference-count":16,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T00:00:00Z","timestamp":1562630400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"},{"start":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T00:00:00Z","timestamp":1562630400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951119001550_as1\"><jats:title>Objective:<\/jats:title><jats:p>To report on the first 5 years of establishment of fetal echocardiographic services at the Jordan University Hospital with emphasis on diagnosis and outcome.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951119001550_as2\"><jats:title>Methods:<\/jats:title><jats:p>A retrospective chart review was conducted on all fetal echocardiographic studies performed between January 2011 and December 2015. Data collected included maternal demographics, referral indications, fetal cardiac diagnosis, correlation to post-natal diagnosis, outcome of pregnancy including pre-mature delivery and perinatal mortality. Basic statistical analysis was performed including demographic analysis, and calculation of fetal echocardiographic sensitivity and specificity.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951119001550_as3\"><jats:title>Results:<\/jats:title><jats:p>A total of 208 fetuses underwent fetal echocardiographic evaluation at a mean gestational age of 26.5 (\u00b15) weeks. The most common referral indication was a suspicion of CHD during the obstetric ultrasound (44.2%), followed by cardiac dysfunction (18.2%), and a family history of CHD (14.9%). Fetal echocardiography showed CHD in 71 fetuses (34%), heart failure in 26 (12.5%), arrhythmia in 9 (4.3%), and intracardiac masses in 2. In the remaining 100 fetuses (48%), fetal echocardiography showed normal evaluation. For detecting CHD, fetal echocardiography had a sensitivity and specificity of 91.7% and 95.4%, respectively. Perinatal mortality including termination of pregnancy, intrauterine fetal death, and neonatal mortality was highest in heart failure (77%), and was 41% for CHD.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951119001550_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>The fetal cardiac diagnostic services at the Jordan University Hospital have encouraging initial results with a relatively high sensitivity and specificity. The services further positively impacted the quality of counselling offered and facilitated pre- and post-natal management.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951119001550","type":"journal-article","created":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T05:09:51Z","timestamp":1562648991000},"page":"1072-1077","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":9,"title":["Prenatal detection of fetal heart disease at Jordan University Hospital: early experience in a developing country"],"prefix":"10.1017","volume":"29","author":[{"given":"Laila","family":"Tutunji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fida","family":"Thekrallah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asma","family":"Basha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bushra","family":"Awaysheh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shorouq","family":"Amer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Khatib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lubna","family":"Hamdan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nisreen","family":"Saber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asma","family":"Mustafa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rama","family":"Jadallah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fawaz","family":"Kazaleh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manar","family":"Al-Lawama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eman","family":"Badran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1388-3100","authenticated-orcid":false,"given":"Iyad","family":"AL-Ammouri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2019,7,9]]},"reference":[{"key":"S1047951119001550_ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2011.02039.x"},{"key":"S1047951119001550_ref9","doi-asserted-by":"publisher","DOI":"10.1159\/000100782"},{"key":"S1047951119001550_ref3","first-page":"159","article-title":"Congenital heart disease at a tertiary care center in Lebanon","volume":"15","author":"Bitar","year":"1999","journal-title":"Middle East J Anaesthesiol"},{"key":"S1047951119001550_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.08.025"},{"key":"S1047951119001550_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01886-7"},{"key":"S1047951119001550_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5273(97)00067-3"},{"key":"S1047951119001550_ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-012-0504-4"},{"key":"S1047951119001550_ref13","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000437597.44550.5d"},{"key":"S1047951119001550_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)01167-8"},{"key":"S1047951119001550_ref14","doi-asserted-by":"publisher","DOI":"10.1111\/ped.12467"},{"key":"S1047951119001550_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/BF02724187"},{"key":"S1047951119001550_ref12","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1071"},{"key":"S1047951119001550_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2009.11.006"},{"key":"S1047951119001550_ref5","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951113001418"},{"key":"S1047951119001550_ref6","doi-asserted-by":"publisher","DOI":"10.3923\/jms.2008.547.552"},{"key":"S1047951119001550_ref7","first-page":"109","article-title":"Incidence of congenital heart disease in Jordanian children born at Jordan University Hospital; A seven-year retrospective study","volume":"51","author":"AL-ammouri","year":"2017","journal-title":"Jordan Med J"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951119001550","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,27]],"date-time":"2019-08-27T09:20:46Z","timestamp":1566897646000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951119001550\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,9]]},"references-count":16,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["S1047951119001550"],"URL":"https:\/\/doi.org\/10.1017\/s1047951119001550","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,9]]},"assertion":[{"value":"\u00a9 Cambridge University Press 2019\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}