{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T22:12:43Z","timestamp":1759011163337,"version":"3.40.5"},"reference-count":26,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2020,2,3]],"date-time":"2020-02-03T00:00:00Z","timestamp":1580688000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951120000177_as1\" sec-type=\"other\"><jats:title>Introduction:<\/jats:title><jats:p>Infants undergoing stage 1 palliation for hypoplastic left heart syndrome may have post-operative feeding difficulties. Although the cause of feeding difficulties in these patients is multi-factorial, residual arch obstruction may affect gut perfusion, contributing to feeding intolerance. We hypothesised that undergoing arch reintervention following stage 1 palliation would be associated with post-operative feeding difficulties.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951120000177_as2\" sec-type=\"other\"><jats:title>Methods:<\/jats:title><jats:p>This was a retrospective cohort study. We analysed data from the National Pediatric Cardiology Quality Improvement Collaborative, which maintains a multicentre registry for infants with hypoplastic left heart syndrome discharged home following stage 1 palliation. Patients who underwent arch reintervention (percutaneous or surgical) prior to discharge following stage 1 palliation were compared with those who underwent non-aortic arch interventions after stage 1 palliation and those who underwent no intervention. Median post-operative days to full enteral feeds and weight for age z-scores were compared. Predictors of post-operative days to full feeds were identified.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951120000177_as3\" sec-type=\"other\"><jats:title>Results:<\/jats:title><jats:p>Among patients who underwent arch reintervention, post-operative days to full enteral feeds were greater than for those who underwent non-aortic arch interventions (25 versus 16, p = 0.003) or no intervention (median days 25 versus 12, p &lt; 0.001). Arch intervention, multiple interventions, gestational age, and the presence of a gastrointestinal anomaly were predictors of days to full feeds.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951120000177_as4\" sec-type=\"other\"><jats:title>Conclusions:<\/jats:title><jats:p>Repeat arch intervention is associated with a longer time to achieve full enteral feeding in patients with hypoplastic left heart syndrome after stage 1 palliation. Further investigation of this association is needed to understand the role of arch obstruction in feeding problems in these patients.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951120000177","type":"journal-article","created":{"date-parts":[[2020,2,3]],"date-time":"2020-02-03T04:24:55Z","timestamp":1580703895000},"page":"396-401","source":"Crossref","is-referenced-by-count":7,"title":["Arch intervention following stage 1 palliation in hypoplastic left heart syndrome is associated with slower feed advancement: a report from the National Pediatric Quality Cardiology Improvement Collaborative"],"prefix":"10.1017","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5372-7487","authenticated-orcid":false,"given":"Alicia H.","family":"Chaves","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carissa M.","family":"Baker-Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geoffrey L.","family":"Rosenthal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2020,2,3]]},"reference":[{"key":"S1047951120000177_ref25","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e318198b167"},{"key":"S1047951120000177_ref24","first-page":"373","article-title":"Reducing the incidence of necrotizing enterocolitis in neonates with hypoplastic left heart syndrome with the introduction of an enteral feed protocol","volume":"11","author":"del Castillo","year":"2010","journal-title":"Pediatr Crit Care 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of oral feeding difficulty in cardiac surgical infants","volume":"29","author":"Einarson","year":"2003","journal-title":"Pediatr 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syndrome","volume":"40","author":"Januszewska","year":"2011","journal-title":"Eur J Cardio-Thoracic Surg"},{"key":"S1047951120000177_ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-012-0396-3"}],"container-title":["Cardiology in the 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