{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T23:33:45Z","timestamp":1787960025150,"version":"build-2784847793"},"reference-count":40,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T00:00:00Z","timestamp":1595808000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951120002097_as1\"><jats:title>Introduction:<\/jats:title><jats:p>We evaluated the safety and feasibility of high-intensity interval training via a novel telemedicine ergometer (MedBIKE\u2122) in children with Fontan physiology.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951120002097_as2\"><jats:title>Methods:<\/jats:title><jats:p>The MedBIKE\u2122 is a custom telemedicine ergometer, incorporating a video game platform and live feed of patient video\/audio, electrocardiography, pulse oximetry, and power output, for remote medical supervision and modulation of work. There were three study phases: (I) exercise workload comparison between the MedBIKE\u2122 and a standard cardiopulmonary exercise ergometer in 10 healthy adults. (II) In-hospital safety, feasibility, and user experience (via questionnaire) assessment of a MedBIKE\u2122 high-intensity interval training protocol in children with Fontan physiology. (III) Eight-week home-based high-intensity interval trial programme in two participants with Fontan physiology.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951120002097_as3\"><jats:title>Results:<\/jats:title><jats:p>There was good agreement in oxygen consumption during graded exercise at matched work rates between the cardiopulmonary exercise ergometer and MedBIKE\u2122 (1.1 \u00b1 0.5 L\/minute versus 1.1 \u00b1 0.5 L\/minute, p = 0.44). Ten youth with Fontan physiology (11.5 \u00b1 1.8 years old) completed a MedBIKE\u2122 high-intensity interval training session with no adverse events. The participants found the MedBIKE\u2122 to be enjoyable and easy to navigate. In two participants, the 8-week home-based protocol was tolerated well with completion of 23\/24 (96%) and 24\/24 (100%) of sessions, respectively, and no adverse events across the 47 sessions in total.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951120002097_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>The MedBIKE\u2122 resulted in similar physiological responses as compared to a cardiopulmonary exercise test ergometer and the high-intensity interval training protocol was safe, feasible, and enjoyable in youth with Fontan physiology. A randomised-controlled trial of a home-based high-intensity interval training exercise intervention using the MedBIKE\u2122 will next be undertaken.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951120002097","type":"journal-article","created":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T12:37:06Z","timestamp":1595853426000},"page":"1409-1416","source":"Crossref","is-referenced-by-count":25,"title":["Cardiac rehabilitation in the paediatric Fontan population: development of a home-based high-intensity interval training programme"],"prefix":"10.1017","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6112-6860","authenticated-orcid":false,"given":"Michael","family":"Khoury","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devin B.","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter 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