{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T00:19:10Z","timestamp":1648945150633},"reference-count":22,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T00:00:00Z","timestamp":1600992000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951120002954_as1\"><jats:title>Background:<\/jats:title><jats:p>In children, the first episode of supraventricular tachycardia occurs at various ages. The aim of this study is to describe age-specific tachycardia mechanisms, clinical findings, and outcome in a contemporary cohort of paediatric patients with supraventricular tachycardia.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951120002954_as2\"><jats:title>Methods:<\/jats:title><jats:p>Retrospective analysis of 531 consecutive patients with structurally normal hearts under the age of 18 years who underwent invasive electrophysiological study for supraventricular tachycardia. The study population was divided into two groups, early-onset group (n = 57) and late-onset group (n = 474), according to the age of the occurrence of the first tachycardia before or after the age of 12 months.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951120002954_as3\"><jats:title>Results:<\/jats:title><jats:p>Accessory pathway-mediated tachycardia was more common (82.5 versus 50.1%, p &lt; 0.001) and the proportion of left-sided accessory pathways was more pronounced (74.5 versus 53.7%, p = 0.01) in the early-onset group than in the late-onset group. The antegrade and retrograde refractory periods of the accessory pathways were similar in both groups, but pre-excitation was more common in the early-onset group (50.9 versus 31.9%, p = 0.007). Typical atrioventricular nodal re-entrant tachycardia was more common (36.7 versus 7.0%, p &lt; 0.001) in the late-onset group. There was no difference among the two groups regarding overall outcome.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951120002954_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>Accessory pathway-mediated re-entrant tachycardia is the most common mechanism of recurrent supraventricular tachycardia in infants with structurally normal hearts who are later referred to an electrophysiological study. These pathways often cause pre-excitation and tend to be located on the left side whereas their refractory period is not different from that of patients with late-onset tachycardia.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951120002954","type":"journal-article","created":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T08:37:26Z","timestamp":1601023046000},"page":"1383-1388","source":"Crossref","is-referenced-by-count":0,"title":["Radiofrequency catheter ablation for supraventricular tachycardia in a paediatric population: characteristics of tachycardia mechanisms in a subpopulation with early onset"],"prefix":"10.1017","volume":"30","author":[{"given":"Yamina","family":"Schibli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Gass","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Berger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Balmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2020,9,25]]},"reference":[{"key":"S1047951120002954_ref20","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1093\/europace\/euu087","article-title":"Long-term results of paediatric radiofrequency catheter ablation: a population-based study","volume":"16","author":"Kubu\u0161","year":"2014","journal-title":"EP Europace"},{"key":"S1047951120002954_ref3","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1136\/hrt.2005.069245","article-title":"Invasive electrophysiology in paediatric and congenital heart disease","volume":"93","author":"Abrams","year":"2007","journal-title":"Heart."},{"key":"S1047951120002954_ref16","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1016\/S0002-9149(99)80303-8","article-title":"Age- and anesthesia-related changes in accessory pathway conduction in children with Wolff-Parkinson-White syndrome","volume":"76","author":"Chang","year":"1995","journal-title":"Am J Cardiol."},{"key":"S1047951120002954_ref2","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.1016\/j.hrthm.2016.06.006","article-title":"Postnatal cumulative incidence of supraventricular tachycardia in a general pediatric population: a national birth cohort database study","volume":"13","author":"Wu","year":"2016","journal-title":"Heart Rhythm."},{"key":"S1047951120002954_ref22","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0735-1097(96)00487-1","article-title":"Electrophysiologic properties of the atrioventricular node in pediatric patients","volume":"29","author":"Cohen","year":"1997","journal-title":"J Am Coll Cardiol."},{"key":"S1047951120002954_ref15","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1159\/000174503","article-title":"Relationship between age and anterograde refractoriness of the accessory pathway in Wolff-Parkinson-White patients","volume":"76","author":"Michelucci","year":"1989","journal-title":"Cardiology."},{"key":"S1047951120002954_ref17","doi-asserted-by":"crossref","first-page":"507","DOI":"10.3345\/kjp.2011.54.12.507","article-title":"Wolff-Parkinson-White syndrome in young people, from childhood to young adulthood: relationships between age and clinical and electrophysiological findings","volume":"54","author":"Jung","year":"2011","journal-title":"Korean J Pediatr."},{"key":"S1047951120002954_ref7","first-page":"e31","article-title":"Living Anatomy of the Atrioventricular Junctions. A Guide to Electrophysiologic Mapping","volume":"100","author":"Cos\u00edo Francisco","year":"1999","journal-title":"Circulation."},{"key":"S1047951120002954_ref19","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1161\/01.CIR.52.4.563","article-title":"Refractory periods of the accessory pathway in the Wolff-Parkinson-White syndrome","volume":"52","author":"Tonkin","year":"1975","journal-title":"Circulation."},{"key":"S1047951120002954_ref6","volume-title":"Heart Disease in Infants, Children, and Adolescents: Including the Fetus and Young Adult","author":"Cannon","year":"2013"},{"key":"S1047951120002954_ref18","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1161\/01.CIR.60.7.1487","article-title":"Wolff-Parkinson-White syndrome in children: electrophysiologic and pharmacologic characteristics","volume":"60","author":"Gillette","year":"1979","journal-title":"Circulation."},{"key":"S1047951120002954_ref12","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/0735-1097(90)90555-4","article-title":"Supraventricular tachycardia due to Wolff-Parkinson-White syndrome in children: early disappearance and late recurrence","volume":"16","author":"Perry","year":"1990","journal-title":"J Am Coll Cardiol."},{"key":"S1047951120002954_ref5","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/S0735-1097(85)80095-4","article-title":"Wolff-Parkinson-White syndrome and supraventricular tachycardia during infancy: management and follow-up","volume":"5","author":"Deal","year":"1985","journal-title":"J. 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