{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T15:05:58Z","timestamp":1761491158646,"version":"3.40.5"},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T00:00:00Z","timestamp":1611532800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>There is minimal data regarding antegrade-only accessory pathways in young patients. Given evolving recommendations and treatments, retrospective analysis of the clinical and electrophysiologic properties of antegrade-only pathways in patients &lt;21 years old was performed, with subsequent comparison of electrophysiology properties to age-matched controls with bidirectional pathways. Of 522 consecutive young patients with ventricular pre-excitation referred for electrophysiology study, 33 (6.3%) had antegrade-only accessory pathways. Indications included palpitations (47%), chest pain (25%), and syncope (22%). The shortest value for either the accessory pathway effective refractory period or the pre-excited R-R interval was taken for each patient, with the median of the antegrade-only group significantly greater than shortest values for the bidirectional group (310 [280\u2013360] ms versus 270 [240\u2013302] ms, p &lt; 0.001). However, the prevalence of pathways with high-risk properties (effective refractory period or shortest pre-excited R-R interval &lt;250 ms) was similar in both study patients and controls (13% versus 21%) (p = 0.55). Sixteen patients had a single antegrade-only accessory pathway and no inducible arrhythmia. Six patients had Mahaim fibres, all right anterolateral with inducible antidromic reciprocating tachycardia. However, 11 patients with antegrade-only accessory pathways and 3 with Mahaim fibres had inducible tachycardia due to a second substrate recognised at electrophysiology study. These included concealed accessory pathways (7), bidirectional accessory pathways (5), and atrioventricular node re-entry (2). Antegrade-only accessory pathways require comprehensive electrophysiology evaluation as confounding factors such as high-risk conduction properties or inducible Supraventricular Tachycardia (SVT) due to a second substrate of tachycardia are often present.<\/jats:p>","DOI":"10.1017\/s1047951121000056","type":"journal-article","created":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T08:54:19Z","timestamp":1611564859000},"page":"1258-1262","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Characteristics of antegrade-only accessory pathways in children and adolescents"],"prefix":"10.1017","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8015-6838","authenticated-orcid":false,"given":"Minh B.","family":"Nguyen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allison C.","family":"Hill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaniv","family":"Bar-Cohen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Silka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2021,1,25]]},"reference":[{"key":"S1047951121000056_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2019.05.058"},{"key":"S1047951121000056_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2017.10.009"},{"key":"S1047951121000056_ref15","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.110.958660"},{"key":"S1047951121000056_ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2010.02880.x"},{"key":"S1047951121000056_ref14","doi-asserted-by":"publisher","DOI":"10.1002\/joa3.12162"},{"key":"S1047951121000056_ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-019-02110-6"},{"key":"S1047951121000056_ref1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a015095"},{"key":"S1047951121000056_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(83)90125-X"},{"key":"S1047951121000056_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2012.03.050"},{"key":"S1047951121000056_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(86)90681-8"},{"key":"S1047951121000056_ref2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.62.6.1335"},{"key":"S1047951121000056_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2012.10.025"},{"key":"S1047951121000056_ref7","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.64.1.176"},{"key":"S1047951121000056_ref9","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.113.000930"},{"key":"S1047951121000056_ref8","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euu191"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951121000056","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,8]],"date-time":"2022-02-08T10:46:51Z","timestamp":1644317211000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951121000056\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,25]]},"references-count":15,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["S1047951121000056"],"URL":"https:\/\/doi.org\/10.1017\/s1047951121000056","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"type":"print","value":"1047-9511"},{"type":"electronic","value":"1467-1107"}],"subject":[],"published":{"date-parts":[[2021,1,25]]},"assertion":[{"value":"\u00a9 The Author(s), 2021. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}