{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T21:58:14Z","timestamp":1747173494880,"version":"3.40.5"},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2021,3,22]],"date-time":"2021-03-22T00:00:00Z","timestamp":1616371200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951121000950_as1\"><jats:title>Background:<\/jats:title><jats:p>Cardiac dysfunction, arrhythmia, and hepatic fibrosis are well-known complications after right heart bypass surgery in patients with single-ventricle physiology. However, little is known about coronary arterial fistulae, and only a few reports have been published. This study aimed to elucidate the clinical characteristics of these rare coronary arterial fistulae that developed as complications in cases of single-ventricle physiology after right heart bypass surgery.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121000950_as2\"><jats:title>Methods:<\/jats:title><jats:p>We retrospectively investigated the clinical features and courses of patients who developed acquired and progressive coronary arterial fistulae after right heart bypass surgery in our hospital.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121000950_as3\"><jats:title>Results:<\/jats:title><jats:p>We identified three cases of coronary arterial fistulae out of 21 patients who underwent right heart bypass surgery. All three cases underwent cardiac catheterisation for post-operative evaluation and were administered pulmonary vasodilators of phosphodiesterase type V inhibitors, antiplatelet, anticoagulation, and diuretics. Moreover, they had common clinical features such as right-dominant single ventricle and long-term exposure to chronic hypoxia. Serial angiograms revealed acquired and progressive coronary arterial fistulae. In addition, coronary arterial fistulae contributed to their symptoms of heart failure.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121000950_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>Patients with chronic hypoxia and dominant right ventricle, who are treated with phosphodiesterase type V inhibitors, should be followed up after right heart bypass surgery to monitor the possible development of coronary arterial fistulae. Moreover, the indication for pulmonary vasodilators in single-ventricle physiology after right heart bypass surgery should be optimised to avoid adverse effects.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951121000950","type":"journal-article","created":{"date-parts":[[2021,3,22]],"date-time":"2021-03-22T06:08:16Z","timestamp":1616393296000},"page":"1823-1828","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Acquired and progressive coronary arterial fistulae in patients with single-ventricle physiology and treated with pulmonary vasodilators"],"prefix":"10.1017","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6410-0874","authenticated-orcid":false,"given":"Kanta","family":"Kishi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Katayama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shintaro","family":"Nemoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriyasu","family":"Ozaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Odanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsuko","family":"Ashida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayato","family":"Konishi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Ashida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2021,3,22]]},"reference":[{"key":"S1047951121000950_ref16","doi-asserted-by":"publisher","DOI":"10.1111\/eci.12636"},{"key":"S1047951121000950_ref10","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-012513-104720"},{"key":"S1047951121000950_ref4","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12457"},{"key":"S1047951121000950_ref8","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00916.2003"},{"key":"S1047951121000950_ref21","first-page":"380","article-title":"Propranolol as a treatment for multiple coronary artery micro-fistulas","volume":"25","author":"Hern\u00e1ndez","year":"2015","journal-title":"CardiolYoung"},{"key":"S1047951121000950_ref13","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.90474.2008"},{"key":"S1047951121000950_ref6","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951110001125"},{"key":"S1047951121000950_ref18","doi-asserted-by":"publisher","DOI":"10.1084\/jem.47.2.293"},{"key":"S1047951121000950_ref17","doi-asserted-by":"publisher","DOI":"10.1159\/000492547"},{"key":"S1047951121000950_ref20","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12077"},{"key":"S1047951121000950_ref11","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25322"},{"key":"S1047951121000950_ref2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2004.051789"},{"key":"S1047951121000950_ref14","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.109.201327"},{"key":"S1047951121000950_ref12","first-page":"1900","article-title":"Comparison of angiogenic and proliferative effects of three commonly used agents for pulmonary artery hypertension (sildenafil, iloprost, bosentan): is angiogenesis always beneficial?","volume":"19","author":"Doganci","year":"2015","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"S1047951121000950_ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-017-1749-8"},{"key":"S1047951121000950_ref15","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9532381"},{"key":"S1047951121000950_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2010.01.045"},{"key":"S1047951121000950_ref5","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12067"},{"key":"S1047951121000950_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.07.065"},{"key":"S1047951121000950_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2016.07.038"},{"key":"S1047951121000950_ref9","doi-asserted-by":"publisher","DOI":"10.1002\/1098-2353(200103)14:2<102::AID-CA1018>3.0.CO;2-4"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951121000950","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T13:16:46Z","timestamp":1637327806000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951121000950\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,22]]},"references-count":21,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["S1047951121000950"],"URL":"https:\/\/doi.org\/10.1017\/s1047951121000950","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"type":"print","value":"1047-9511"},{"type":"electronic","value":"1467-1107"}],"subject":[],"published":{"date-parts":[[2021,3,22]]},"assertion":[{"value":"\u00a9 The Author(s), 2021. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}