{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T23:12:08Z","timestamp":1785798728056,"version":"3.56.0"},"reference-count":9,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T00:00:00Z","timestamp":1618185600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Platypnea\u2013orthodeoxia syndrome is a rare clinical entity characterised by positional dyspnoea and arterial desaturation while in the upright position, the symptoms generally occurring in adults. We describe a 12-year-old girl diagnosed with platypnea\u2013orthodeoxia syndrome associated with patent foramen ovale. The symptoms resolved following percutaneous patent foramen ovale closure.<\/jats:p>","DOI":"10.1017\/s1047951121001396","type":"journal-article","created":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T16:37:16Z","timestamp":1618245436000},"page":"1706-1708","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":4,"title":["Platypnea\u2013orthodeoxia syndrome in a child: relief of symptoms after transcatheter closure of patent foramen ovale"],"prefix":"10.1017","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6827-5527","authenticated-orcid":false,"given":"Nil\u00fcfer","family":"Cetiner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeynep Seda","family":"Uyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alpay","family":"Celiker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2021,4,12]]},"reference":[{"key":"S1047951121001396_ref7","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1002\/(SICI)1522-726X(199905)47:1<64::AID-CCD15>3.0.CO;2-6","article-title":"Platypnea-orthodeoxia syndrome: etiology, differential diagnosis, and management","volume":"47","author":"Cheng","year":"1999","journal-title":"Catheter Cardiovasc Interventions Off J Soc Cardiac Angiogr Interventions"},{"key":"S1047951121001396_ref8","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.hrtlng.2007.09.006","article-title":"Hypoxemia-orthodeoxia related to patent foramen ovale without pulmonary hypertension","volume":"37","author":"Toffart","year":"2008","journal-title":"Heart Lung"},{"key":"S1047951121001396_ref5","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1016\/0002-9149(83)90238-2","article-title":"Platypnea and interatrial right-to-left shunting after lobectomy","volume":"51","author":"Springer","year":"1983","journal-title":"Am J Cardiol"},{"key":"S1047951121001396_ref9","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1007\/s00270-004-0035-3","article-title":"Transcatheter closure of patent foramen ovale in patients with platypnea\u2013orthodeoxia: results of a multicentric french registry","volume":"28","author":"Guerin","year":"2005","journal-title":"Cardiovasc Intervent Radiol"},{"key":"S1047951121001396_ref1","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0025-6196(12)61253-1","article-title":"Platypnea-orthodeoxia: Clinical profile, diagnostic workup, management, and report of seven cases","volume":"59","author":"Seward","year":"1984","journal-title":"Mayo Clin Proc"},{"key":"S1047951121001396_ref6","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1136\/hrt.2003.027839","article-title":"Hypoxaemia associated with an enlarged aortic root: a new syndrome?","volume":"91","author":"Eicher","year":"2005","journal-title":"Heart"},{"key":"S1047951121001396_ref3","doi-asserted-by":"crossref","first-page":"e15","DOI":"10.1016\/j.jacc.2013.02.097","article-title":"Platypnea-orthodeoxia syndrome: insight of mechanism from imaging","volume":"62","author":"Yoshida","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"S1047951121001396_ref2","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.ejim.2015.09.017","article-title":"Patent foramen ovale: unanswered questions","volume":"26","author":"Mojadidi","year":"2015","journal-title":"Eur J Intern Med"},{"key":"S1047951121001396_ref4","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1378\/chest.100.4.1157","article-title":"Patent foramen ovale associated with platypnea and orthodeoxia","volume":"100","author":"Sorrentino","year":"1991","journal-title":"Chest"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951121001396","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T13:18:32Z","timestamp":1647350312000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951121001396\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,12]]},"references-count":9,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["S1047951121001396"],"URL":"https:\/\/doi.org\/10.1017\/s1047951121001396","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,12]]},"assertion":[{"value":"\u00a9 The Author(s), 2021. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}