{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T17:57:35Z","timestamp":1764784655932,"version":"3.40.5"},"reference-count":14,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T00:00:00Z","timestamp":1620086400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951121001499_as1\"><jats:title>Background:<\/jats:title><jats:p>Prior to the recent release of appropriate use criteria for imaging valvulopathies in children, follow-up of valvular lesions, including isolated bicuspid aortic valve, was not standardised. We describe current follow up, treatment, and intervention strategies for isolated bicuspid aortic valve with varying degrees of stenosis, regurgitation, and dilation in children up to 18 years old and compare them with newly released appropriate use criteria.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121001499_as2\"><jats:title>Methods:<\/jats:title><jats:p>Online survey was sent to members of the American Academy of Pediatrics Section on Cardiology and Cardiac Surgery and PediHeartNet.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121001499_as3\"><jats:title>Results:<\/jats:title><jats:p>Totally, 106 responses with interpretable data were received. For asymptomatic patients with isolated BAV without stenosis, regurgitation, or dilation follow-up-intervals increased from 7+\/\u22124 months in the newborn period to 28 +\/\u2212 14 months at 18 years of age. Respondents recommended more frequent follow-up for younger patients and those with greater disease severity. More than 80% of respondents treat aortic regurgitation or aortic dilation in the setting of bicuspid aortic valve medically. In general, intervention was recommended once stenosis or regurgitation became severe (stenosis of &gt;4 m\/s; regurgitation with LV Z score 4) regardless of age, but was not routinely recommended for younger children (newborn \u2013 age 6 years) with severe dilation. Exercise was restricted at 38+\/\u221211 mmHg echocardiographic mean gradient.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121001499_as4\"><jats:title>Conclusions:<\/jats:title><jats:p>Current follow-up, treatment, and intervention strategies for isolated bicuspid aortic valve deviate from appropriate use criteria. Differences between the two highlight the need to better delineate the disease course, clarify recommendations for care, and encourage wider adoption of guidelines.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951121001499","type":"journal-article","created":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T08:47:14Z","timestamp":1620118034000},"page":"24-30","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":3,"title":["Variation in management of paediatric isolated bicuspid aortic valve: current practice survey"],"prefix":"10.1017","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8983-3329","authenticated-orcid":false,"given":"Jesse M.","family":"Boyett Anderson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John S","family":"Hokanson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2021,5,4]]},"reference":[{"key":"S1047951121001499_ref12","first-page":"1","article-title":"Exercise and activity reccommendations in children after cardiac surgery: current practice survey","volume":"18","author":"Boyett Anderson","year":"2020","journal-title":"Congenit Cardiol Today."},{"key":"S1047951121001499_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.02.536"},{"key":"S1047951121001499_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.05.021"},{"key":"S1047951121001499_ref5","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.jacc.2017.03.011","article-title":"AHA\/ACC Focused Update of the 2014 AHA\/ACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines","volume":"70","author":"Nishimura","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"S1047951121001499_ref6","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1016\/j.jacc.2017.07.732","article-title":"ACC\/AATS\/AHA\/ASE\/ASNC\/HRS\/SCAI\/SCCT\/SCMR\/STS 2017 Appropriate Use Criteria for Multimodality Imaging in Valvular Heart Disease: A Report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and Society of Thoracic Surgeons","volume":"70","author":"Doherty","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"S1047951121001499_ref7","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/s00246-013-0856-4","article-title":"Clinical outcome, valve dysfunction, and progressive aortic dilation in a pediatric population with isolated bicuspid aortic valve","volume":"35","author":"Spaziani","year":"2014","journal-title":"Pediatr Cardiol"},{"key":"S1047951121001499_ref2","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1136\/heart.83.1.81","article-title":"Clinical significance of the bicuspid aortic valve","volume":"83","author":"Ward","year":"2000","journal-title":"Heart"},{"key":"S1047951121001499_ref9","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12591"},{"key":"S1047951121001499_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.10.002"},{"key":"S1047951121001499_ref14","doi-asserted-by":"crossref","first-page":"2398","DOI":"10.1016\/j.jacc.2015.09.039","article-title":"Eligibility and Disqualification Recommendations for Competitive Athletes With Cardiovascular Abnormalities: Task Force 7: Aortic Diseases, Including Marfan Syndrome: A Scientific Statement From the American Heart Association and American College of Cardiology","volume":"66","author":"Braverman","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"S1047951121001499_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2003.11.031"},{"key":"S1047951121001499_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2020.02.039"},{"key":"S1047951121001499_ref3","doi-asserted-by":"publisher","DOI":"10.1542\/peds.105.4.815"},{"key":"S1047951121001499_ref8","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.081539"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951121001499","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,13]],"date-time":"2022-10-13T08:24:35Z","timestamp":1665649475000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951121001499\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,4]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["S1047951121001499"],"URL":"https:\/\/doi.org\/10.1017\/s1047951121001499","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"type":"print","value":"1047-9511"},{"type":"electronic","value":"1467-1107"}],"subject":[],"published":{"date-parts":[[2021,5,4]]},"assertion":[{"value":"\u00a9 The Author(s), 2021. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}