{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:46:21Z","timestamp":1786999581709,"version":"build-2736575974"},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T00:00:00Z","timestamp":1627862400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2022,5]]},"abstract":"Abstract<\/jats:title>\n \n Objectives:<\/jats:title>\n Aortic valve repair in children is still a challenge. The aim of this study was to analyse the surgical results of children with aortic regurgitation who underwent single leaflet reconstruction using the Ozaki procedure in our medical centre.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n A retrospective study was conducted of nine children with aortic regurgitation who received single leaflet reconstruction from May 2017 to September 2019. Paired t-tests and Wilcoxon signed rank tests were used to compare the data at different time points.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n The median surgical age was 4.7 (3.5, 6.4) years. Eight patients were pre-operatively diagnosed with severe aortic regurgitation, while one had moderate regurgitation. The left ventricles were significantly enlarged, with an average z-score of 3.8. Single leaflet reconstruction was carried out using glutaraldehyde-treated autologous pericardium under the standard Ozaki procedure. The median follow-up was 22 (14, 33) months. There was no post-operative death or re-intervention. One patient had moderate or more aortic regurgitation during the follow-up. The average degree of aortic regurgitation was mild, and the average z-score of the left ventricle decreased to \u22120.2 in the last follow-up.<\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n Single leaflet reconstruction using the Ozaki procedure was an effective surgical method for treating children with aortic regurgitation in our centre with satisfactory short-term results.<\/jats:p>\n <\/jats:sec>","DOI":"10.1017\/s1047951121003164","type":"journal-article","created":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T04:33:31Z","timestamp":1627878811000},"page":"789-793","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":4,"title":["Single leaflet reconstruction in paediatric aortic regurgitation using the Ozaki procedure"],"prefix":"10.1017","volume":"32","author":[{"given":"Tao","family":"Shi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoujun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8660-0485","authenticated-orcid":false,"given":"Zhongdong","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2021,8,2]]},"reference":[{"key":"S1047951121003164_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2018.01.087"},{"key":"S1047951121003164_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2020.01.087"},{"key":"S1047951121003164_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2007.10.037"},{"key":"S1047951121003164_ref13","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezr214"},{"key":"S1047951121003164_ref3","doi-asserted-by":"publisher","DOI":"10.1510\/icvts.2010.253682"},{"key":"S1047951121003164_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2012.11.012"},{"key":"S1047951121003164_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2013.04.085"},{"key":"S1047951121003164_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2020.06.145"},{"key":"S1047951121003164_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2006.01.068"},{"key":"S1047951121003164_ref11","doi-asserted-by":"publisher","DOI":"10.1053\/j.pcsu.2017.11.009"},{"key":"S1047951121003164_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2019.09.176"},{"key":"S1047951121003164_ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-014-1019-y"},{"key":"S1047951121003164_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2005.04.041"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951121003164","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T04:22:14Z","timestamp":1652761334000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951121003164\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,2]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["S1047951121003164"],"URL":"https:\/\/doi.org\/10.1017\/s1047951121003164","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,2]]},"assertion":[{"value":"\u00a9 The Author(s), 2021. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}