{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T06:37:32Z","timestamp":1785393452682,"version":"3.55.0"},"reference-count":14,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T00:00:00Z","timestamp":1629849600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951121003498_as1\"><jats:title>Objective:<\/jats:title><jats:p>To investigate the risk factors associated with prolonged ventilation after Fontan surgery.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121003498_as2\"><jats:title>Design:<\/jats:title><jats:p>Retrospective case series.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121003498_as3\"><jats:title>Setting:<\/jats:title><jats:p>Tertiary childrens hospital.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121003498_as4\"><jats:title>Patients:<\/jats:title><jats:p>We included 123 children who underwent Fontan surgery without delayed sternal closure or extracorporeal membrane oxygenation between 2011 and 2017.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121003498_as5\"><jats:title>Intervention:<\/jats:title><jats:p>Fontan surgery.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121003498_as6\"><jats:title>Measurements and main results:<\/jats:title><jats:p>Prolonged ventilation was defined as intubation for more than 24 hours after surgery. Preoperative, intraoperative, and perioperative data were collected retrospectively from medical records. Multivariate logistic regression analysis was used to identify risk factors for prolonged ventilation. The median age and weight of patients were 2.2 years and 10.0 kg, respectively. Seventeen per cent of the patients (n = 21) received prolonged mechanical ventilation, and the median intubation period was 2.9 days. There were no 90-day or in-hospital deaths. The independent predictors of prolonged ventilation identified were fenestration (p &lt; 0.01), low pulmonary artery index (p = 0.02), and advanced atrioventricular regurgitation (p &lt; 0.01). The duration of ICU stay was significantly longer in the prolonged ventilation group than in the early extubation group (10 days versus 6 days, p &lt; 0.01).<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121003498_as7\"><jats:title>Conclusion:<\/jats:title><jats:p>Fenestration, low pulmonary artery index, and significant atrioventricular regurgitation are risk factors for prolonged ventilation after Fontan surgery. Careful preoperative and perioperative management that considers the risk factors for prolonged ventilation in each individual is important.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951121003498","type":"journal-article","created":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T07:53:18Z","timestamp":1629877998000},"page":"969-974","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":3,"title":["Risk factors for prolonged ventilation after the modified Fontan procedure"],"prefix":"10.1017","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2760-6040","authenticated-orcid":false,"given":"Masahiro","family":"Tsubura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Osaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kensaku","family":"Motono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nao","family":"Hamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2021,8,25]]},"reference":[{"key":"S1047951121003498_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2013.11.068"},{"key":"S1047951121003498_ref2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/52.10.999"},{"key":"S1047951121003498_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2012.12.042"},{"key":"S1047951121003498_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2014.06.093"},{"key":"S1047951121003498_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)38300-X"},{"key":"S1047951121003498_ref1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.26.3.240"},{"key":"S1047951121003498_ref3","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.65.4.213"},{"key":"S1047951121003498_ref10","first-page":"29(e16554)","article-title":"Comparison of the fenestrated and non-fenestrated Fontan procedures","volume":"98","author":"Li","year":"2019","journal-title":"Medicine"},{"key":"S1047951121003498_ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8191.2010.01088.x"},{"key":"S1047951121003498_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2010.03.013"},{"key":"S1047951121003498_ref8","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.8.2226"},{"key":"S1047951121003498_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2008.02.010"},{"key":"S1047951121003498_ref12","first-page":"216","article-title":"3rd, etal, pulmonary artery index. a nonpredictor of operative survival in patients undergoing modified Fontan repair","volume":"80","author":"Bridges","year":"1989","journal-title":"Circulation"},{"key":"S1047951121003498_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2019.12.020"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1047951121003498","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T10:16:35Z","timestamp":1655288195000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1047951121003498\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,25]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["S1047951121003498"],"URL":"https:\/\/doi.org\/10.1017\/s1047951121003498","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,25]]},"assertion":[{"value":"\u00a9 The Author(s), 2021. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}