{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T23:57:36Z","timestamp":1785196656660,"version":"3.55.0"},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T00:00:00Z","timestamp":1634688000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S104795112100408X_as1\"><jats:title>Background:<\/jats:title><jats:p>Truncus arteriosus is a rare CHD. Neonatal and early infancy repair is recommended though some cases may present late. The aim of our study is to investigate the current results of truncus arteriosus repair and to analyse the differences in outcome and reintervention need between early versus late truncus arteriosus surgical repair.<\/jats:p><\/jats:sec><jats:sec id=\"S104795112100408X_as2\"><jats:title>Material and methods:<\/jats:title><jats:p>In this cohort study, we reviewed all children who underwent truncus arteriosus repair from 2001 till 2021. We divided patients into two groups; early repair group including patients repaired at age less than 3 months and late repair group including patients who had repair at 3 months of age and later. We compared both groups for outcome variables.<\/jats:p><\/jats:sec><jats:sec id=\"S104795112100408X_as3\"><jats:title>Results:<\/jats:title><jats:p>Sixty-four children had truncus arteriosus repair including 48(75%) patients in early repair and 16(25%) patients in late repair groups. Peri-operative course was comparable between both groups. Post-surgery, we observed pulmonary hypertension in 6(12%) patients in early repair group comparing with 11(69%) patients in late repair group (p = 0.0001). In the last follow-up visit, pulmonary hypertension resolved in all early repair group patients while 6(37.5%) patients in late repair group continued to have pulmonary hypertension (p = 0.0001). Twenty-three(36%) patients required reintervention including 22(48%) in early repair group versus 1(6%) in late repair group (p = 0.007).<\/jats:p><\/jats:sec><jats:sec id=\"S104795112100408X_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>In general, the outcome of early truncus arteriosus repair is excellent with resolution of pulmonary hypertension following early repair. Late repair caries higher risk of persistent pulmonary hypertension (37.5%). About one-third of the patients who had truncus arteriosus repair will require re-intervention within 38\u00b138.4 months after initial surgery.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s104795112100408x","type":"journal-article","created":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T08:56:44Z","timestamp":1634720204000},"page":"1289-1295","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":10,"title":["Outcome of truncus arteriosus repair: 20 years of single-center experience comparing early versus late surgical repair"],"prefix":"10.1017","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1906-4541","authenticated-orcid":false,"given":"Abdah","family":"Hrfi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muna","family":"Ismail","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed H. A.","family":"Mohammed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7297-9137","authenticated-orcid":false,"given":"Hussam K.","family":"Hamadah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1801-5828","authenticated-orcid":false,"given":"Fahad","family":"Alhabshan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riyadh","family":"Abu-Sulaiman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Salim","family":"Kabbani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2021,10,20]]},"reference":[{"key":"S104795112100408X_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2008.06.021"},{"key":"S104795112100408X_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)33777-8"},{"key":"S104795112100408X_ref9","first-page":"124","article-title":"Echocardiography in pediatric pulmonary hypertension","volume":";2","author":"Jone","year":"2014","journal-title":"Front Pediatr"},{"key":"S104795112100408X_ref18","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951117002050"},{"key":"S104795112100408X_ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-008-9328-7"},{"key":"S104795112100408X_ref10","doi-asserted-by":"publisher","DOI":"10.1530\/ERP-17-0071"},{"key":"S104795112100408X_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(96)70346-X"},{"key":"S104795112100408X_ref19","doi-asserted-by":"publisher","DOI":"10.1177\/2150135113516370"},{"key":"S104795112100408X_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(76)80400-0"},{"key":"S104795112100408X_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6109(16)32803-1"},{"key":"S104795112100408X_ref12","first-page":"45","article-title":"Assessment of pulmonary artery pressure by echocardiography-A comprehensive review","volume":"12","author":"Parasuraman","year":"2016","journal-title":"Int J Cardiol Heart Vasc"},{"key":"S104795112100408X_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2016.03.010"},{"key":"S104795112100408X_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2009.09.050"},{"key":"S104795112100408X_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)33780-8"},{"key":"S104795112100408X_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S1058-9813(02)00010-3"},{"key":"S104795112100408X_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(97)01155-X"},{"key":"S104795112100408X_ref7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0146800"},{"key":"S104795112100408X_ref17","doi-asserted-by":"publisher","DOI":"10.1510\/icvts.2010.243410"},{"key":"S104795112100408X_ref11","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-1583"}],"container-title":["Cardiology in the Young"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S104795112100408X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,16]],"date-time":"2022-08-16T08:43:23Z","timestamp":1660639403000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S104795112100408X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,20]]},"references-count":19,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["S104795112100408X"],"URL":"https:\/\/doi.org\/10.1017\/s104795112100408x","relation":{},"ISSN":["1047-9511","1467-1107"],"issn-type":[{"value":"1047-9511","type":"print"},{"value":"1467-1107","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,20]]},"assertion":[{"value":"\u00a9 The Author(s), 2021. 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