{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T06:54:24Z","timestamp":1765608864766,"version":"3.40.5"},"reference-count":43,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2021,10,28]],"date-time":"2021-10-28T00:00:00Z","timestamp":1635379200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951121004509_as1\"><jats:title>Background:<\/jats:title><jats:p>Children with exposure to coronavirus disease 2019 in recent times (asymptomatic or symptomatic infection) approaching congenital heart surgery programme are in increasing numbers. Understanding outcomes of such children will help risk-stratify and guide optimisation prior to congenital heart surgery.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121004509_as2\"><jats:title>Objective:<\/jats:title><jats:p>The objective of the present study was to determine whether convalescent coronavirus disease 2019 children undergoing congenital heart surgery have any worse mortality or post-operative outcomes.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121004509_as3\"><jats:title>Design:<\/jats:title><jats:p>Consecutive children undergoing congenital heart surgery from Oct 2020 to May 2021 were enrolled after testing for reverse transcription-polymerase chain reaction or rapid antigen test and immunoglobulin G antibody prior to surgery. Convalescent coronavirus disease 2019 was defined in any asymptomatic patient positive for immunoglobulin G antibodies and negative for reverse transcription-polymerase chain reaction or rapid antigen test anytime 6 weeks prior to surgery. Control patients were negative for any of the three tests. Mortality and post-operative outcomes were compared among the groups.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121004509_as4\"><jats:title>Results:<\/jats:title><jats:p>One thousand one hundred and twenty-nine consecutive congenital heart surgeries were stratified as convalescence and control. Coronavirus disease 2019 Convalescent (n = 349) and coronavirus disease 2019 control (n = 780) groups were comparable for all demographic and clinical factors except younger and smaller kids in control. Convalescent children had no higher mortality, ventilation duration, ICU and hospital stay, no higher support with extracorporeal membrane oxygenation, high flow nasal cannula, no higher need for re-intubations, re-admissions, and no higher infections as central line-associated bloodstream infection, sternal site infection, and ventilator-associated pneumonia on comparison with coronavirus disease 2019 control children.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121004509_as5\"><jats:title>Conclusions:<\/jats:title><jats:p>Convalescent coronavirus disease 2019 does not have any unfavourable outcomes as compared to coronavirus disease 2019 control children. Positive immunoglobulin G antibody screening prior to surgery is suggestive of convalescence and supports comparable outcomes on par with control peers.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951121004509","type":"journal-article","created":{"date-parts":[[2021,10,28]],"date-time":"2021-10-28T04:53:16Z","timestamp":1635396796000},"page":"1469-1474","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":6,"title":["Coronavirus disease 2019 convalescent children: outcomes after congenital heart surgery"],"prefix":"10.1017","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1073-7631","authenticated-orcid":false,"given":"Shreedhar S.","family":"Joshi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manaswini","family":"Keshava","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keshava S.","family":"Murthy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ganesh","family":"Sambandamoorthy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riyan","family":"Shetty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Balasubramanian","family":"Shanmugasundaram","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4185-6695","authenticated-orcid":false,"given":"Sudesh","family":"Prabhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh","family":"Hegde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vijay S.","family":"Richard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2021,10,28]]},"reference":[{"key":"S1047951121004509_ref16","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1016\/j.athoracsur.2018.05.080","article-title":"Tetralogy of fallot repair in developing countries: international quality improvement collaborative","volume":"106","author":"Sandoval","year":"2018","journal-title":"Ann Thorac Surg"},{"key":"S1047951121004509_ref20","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951120004345"},{"key":"S1047951121004509_ref34","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1055\/s-0041-1729557","article-title":"Neonates born to COVID-19 mother and risk in management within 4 weeks of life: a single-center experience, Systematic review, and meta-analysis","volume":"38","author":"Falsaperla","year":"2021","journal-title":"Am J Perinatol"},{"key":"S1047951121004509_ref4","first-page":"193","article-title":"Clinical and epidemiologic profile of the initial COVID-19 patients at a tertiary care centre in India","volume":"90","author":"Gupta","year":"2020","journal-title":"Monaldi Arch Chest Dis"},{"key":"S1047951121004509_ref29","doi-asserted-by":"crossref","first-page":"e28485","DOI":"10.1002\/pbc.28485","article-title":"COVID-19 anticoagulation recommendations in children","volume":"67","author":"Loi","year":"2020","journal-title":"Pediatr Blood Cancer"},{"volume-title":"The Lancet Infectious Diseases","year":"2021","author":"Huang","key":"S1047951121004509_ref40"},{"key":"S1047951121004509_ref22","doi-asserted-by":"crossref","first-page":"269","DOI":"10.4103\/apc.apc_134_21","article-title":"Outcome of COVID-19-positive children with heart disease and grown-ups with congenital heart disease: a multicentric study from India","volume":"14","author":"Sachdeva","year":"2021","journal-title":"Ann Pediatr Cardiol"},{"key":"S1047951121004509_ref42","unstructured":"42. 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