{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T06:06:32Z","timestamp":1785823592548,"version":"3.56.0"},"reference-count":25,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T00:00:00Z","timestamp":1641427200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951121005126_as1\"><jats:title>Aim:<\/jats:title><jats:p>The left and right ventricular dysfunction are important clinical course indicators in patients with repaired tetralogy of Fallot. This study aimed to evaluate ventricular volumes, functions, and myocardial deformation in children with repaired tetralogy of Fallot by real-time three-dimensional (four-dimensional) echocardiography and compared with healthy children. It also aimed to investigate the relationships between ventricular volumes, functions, and myocardial deformation parameters in the patients.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121005126_as2\"><jats:title>Materials and methods:<\/jats:title><jats:p>In this cross-sectional study, 35 patients (mean age 15.1 \u00b1 2.8 years, 54% male) and 35 healthy controls of similar age, gender, and body measurements underwent echocardiography. End-diastolic volume index, end-systolic volume index, and ejection fractions of both ventricles; global longitudinal, circumferential, radial strain, twist, and torsion of the left ventricle; the longitudinal strain of the right ventricle free wall and septum were measured.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121005126_as3\"><jats:title>Results:<\/jats:title><jats:p>Left ventricular ejection fraction, global circumferential and radial strain, twist and torsion were significantly lower in patients compared with controls. Left ventricular ejection fraction correlated with global circumferential (r = \u22120.446, p &lt; 0.001) and radial strain (r = \u22120.433, p &lt; 0.001) in the patients. Right ventricular volumes were significantly higher, and ejection fraction was significantly lower in patients compared with controls. All right ventricular parameters correlated with each other in the patients.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121005126_as4\"><jats:title>Conclusion:<\/jats:title><jats:p>Left ventricular contraction pattern was changed, circumferential and radial fibres were most affected in the patients. Right ventricular dilatation and dysfunction were detected, and right ventricular ejection fraction correlated well with strain measurements of the right ventricle.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951121005126","type":"journal-article","created":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T06:56:52Z","timestamp":1641452212000},"page":"1901-1909","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of ventricular function and myocardial deformation in children with repaired tetralogy of Fallot by real-time three-dimensional (four-dimensional) echocardiography"],"prefix":"10.1017","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6579-0670","authenticated-orcid":false,"given":"Ay\u015fe G.","family":"Ero\u011flu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3812-2081","authenticated-orcid":false,"given":"Selman","family":"G\u00f6kalp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7319-4139","authenticated-orcid":false,"given":"Sezen U.","family":"Atik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damla","family":"\u00d6nal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hazal C.","family":"Acar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Levent","family":"Salt\u0131k","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2022,1,6]]},"reference":[{"key":"S1047951121005126_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2018.11.004"},{"key":"S1047951121005126_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02714-8"},{"key":"S1047951121005126_ref11","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jet244"},{"key":"S1047951121005126_ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2011.01417.x"},{"key":"S1047951121005126_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2019.07.634"},{"key":"S1047951121005126_ref8","doi-asserted-by":"publisher","DOI":"10.1097\/HCO.0000000000000426"},{"key":"S1047951121005126_ref17","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.59.5.1024"},{"key":"S1047951121005126_ref24","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.108.783795"},{"key":"S1047951121005126_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2011.06.016"},{"key":"S1047951121005126_ref15","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jev014"},{"key":"S1047951121005126_ref21","first-page":"1347","article-title":"Assessment 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2022. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}