{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T18:47:26Z","timestamp":1790275646559,"version":"4.1.0"},"reference-count":28,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T00:00:00Z","timestamp":1641427200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Cardiol Young"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1047951121005138_as1\"><jats:title>Objectives:<\/jats:title><jats:p>Many children diagnosed with COVID-19 infections did not require hospitalisation. Our objective was to analyse electrocardiographic changes in children with asymptomatic, mild or moderate COVID-19 who did not require hospitalisation<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121005138_as2\"><jats:title>Methods:<\/jats:title><jats:p>All children are seen in a paediatric cardiology clinic who had asymptomatic, mild or moderate COVID-19 that did not require hospitalisation and had at least one electrocardiogram after their diagnosis were included in this retrospective analysis. Records were reviewed to determine COVID-19 disease severity and presence of Long COVID. Rhythm assessment, atrial enlargement, ventricular hypertrophy, PR\/QRS\/QT interval duration and ST-T wave abnormalities were analysed by a paediatric electrophysiologist. Clinically ordered echocardiograms were reviewed for signs of myopericarditis (left ventricular ejection fraction and pericardial effusion) on any subject with an electrocardiographic abnormality.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121005138_as3\"><jats:title>Results:<\/jats:title><jats:p>Of the 82 children meeting inclusion criteria (14.4 years, range 1\u201318 years, 57% male), 17 patients (21%) demonstrated electrocardiographic changes. Ten patients (12%) had electrocardiogram of borderline significance, which included isolated mild PR prolongation or mild repolarisation abnormalities. The other seven patients (9%) had concerning electrocardiographic findings consisting of more significant repolarisation abnormalities. None of the patients with an abnormal electrocardiogram revealed any echocardiographic abnormality. All abnormal electrocardiograms normalised over time except in two cases. Across the entire cohort, greater COVID-19 disease severity and long COVID were not associated with electrocardiographic abnormalities.<\/jats:p><\/jats:sec><jats:sec id=\"S1047951121005138_as4\"><jats:title>Conclusions:<\/jats:title><jats:p>Electrocardiographic abnormalities are present in a minority of children with an asymptomatic, mild or moderate COVID-19 infection. Many of these changes resolved over time and no evidence of myopericarditis was present on echocardiography.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1047951121005138","type":"journal-article","created":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T08:01:06Z","timestamp":1641456066000},"page":"1910-1916","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":12,"title":["Electrocardiographic changes in non-hospitalised children with COVID-19"],"prefix":"10.1017","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4423-6782","authenticated-orcid":false,"given":"Howard J.","family":"Heching","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anmol","family":"Goyal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Harvey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsey","family":"Malloy-Walton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1029-800X","authenticated-orcid":false,"given":"Christopher","family":"Follansbee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Mcintosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1999-6509","authenticated-orcid":false,"given":"Daniel","family":"Forsha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2022,1,6]]},"reference":[{"key":"S1047951121005138_ref20","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951121003012"},{"key":"S1047951121005138_ref15","doi-asserted-by":"crossref","first-page":"e2020042929","DOI":"10.1542\/peds.2020-042929","article-title":"30-day outcomes of children and adolescents with COVID-19: an international experience","volume":"148","author":"Talita","year":"2021","journal-title":"Pediatrics"},{"key":"S1047951121005138_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.08.059"},{"key":"S1047951121005138_ref18","first-page":"10","article-title":"Children with long COVID","volume":"249","author":"Thomson","year":"2021","journal-title":"New Sci"},{"key":"S1047951121005138_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2020.05.013"},{"key":"S1047951121005138_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2020.04.048"},{"key":"S1047951121005138_ref27","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12216"},{"key":"S1047951121005138_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30566-3"},{"key":"S1047951121005138_ref9","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2020-0702"},{"key":"S1047951121005138_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjco.2021.02.012"},{"key":"S1047951121005138_ref25","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.3.278"},{"key":"S1047951121005138_ref28","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.055673"},{"key":"S1047951121005138_ref12","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951120005016"},{"key":"S1047951121005138_ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-020-03766-6"},{"key":"S1047951121005138_ref19","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-021-02318-9"},{"key":"S1047951121005138_ref26","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa060781"},{"key":"S1047951121005138_ref22","doi-asserted-by":"publisher","DOI":"10.1007\/BF02083144"},{"key":"S1047951121005138_ref16","first-page":"100764","article-title":"Cardiac abnormalities due to multisystem inflammatory syndrome temporally associated with COVID-19 among children: a systematic review and meta-analysis","volume":"33","author":"Aski","year":"2021","journal-title":"Int J Cardiol Heart Vasc"},{"key":"S1047951121005138_ref2","unstructured":"2. CDC COVID DATA. COVID data tracker weekly review."},{"key":"S1047951121005138_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.08.069"},{"key":"S1047951121005138_ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2014.10.003"},{"key":"S1047951121005138_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2020.12.033"},{"key":"S1047951121005138_ref24","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.2091"},{"key":"S1047951121005138_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2020.06.026"},{"key":"S1047951121005138_ref11","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2020-009704"},{"key":"S1047951121005138_ref10","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2020-009738"},{"key":"S1047951121005138_ref1","unstructured":"1. WHO Director. General\u2019s opening remarks at the media briefing on COVID-19 2020."},{"key":"S1047951121005138_ref21","unstructured":"21. 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